79787-43-2 Usage
Description
3-Hydroxyphencyclidine (3-HO-PCP) is a dissociative hallucinogen belonging to the arylcyclohexylamine class, closely related to phencyclidine (PCP). It has been marketed as a designer drug and has gained attention due to its potential misuse and associated risks.
Used in Research and Forensic Analysis:
3-Hydroxyphencyclidine is used as a research chemical for studying the effects and mechanisms of action of dissociative hallucinogens. It aids in understanding the structure-activity relationships and potential therapeutic applications of these compounds.
Used in Drug Policy and Regulation:
3-Hydroxyphencyclidine is used as a reference point in drug policy and regulation discussions, particularly in the context of the Misuse of Drugs Act (1971) in the United Kingdom. The Advisory Council on the Misuse of Drugs has suggested that 3-HO-PCP and other arylcyclohexamines should be classified as Class B drugs, highlighting the need for a catch-all clause to cover both existing and unresearched compounds in this class.
Check Digit Verification of cas no
The CAS Registry Mumber 79787-43-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,7,8 and 7 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 79787-43:
(7*7)+(6*9)+(5*7)+(4*8)+(3*7)+(2*4)+(1*3)=202
202 % 10 = 2
So 79787-43-2 is a valid CAS Registry Number.
InChI:InChI=1/C17H25NO/c19-16-9-7-8-15(14-16)17(10-3-1-4-11-17)18-12-5-2-6-13-18/h7-9,14,19H,1-6,10-13H2
79787-43-2Relevant articles and documents
Novel analogues of ketamine and phencyclidine as NMDA receptor antagonists
Zarantonello, Paola,Bettini, Ezio,Paio, Alfredo,Simoncelli, Chiara,Terreni, Silvia,Cardullo, Francesco
, p. 2059 - 2063 (2011/04/24)
The identification of structurally novel analogues of ketamine and phencyclidine (PCP), as NMDA receptor antagonists, with low to moderate potency at GluN2A and GluN2B receptors is discussed. In particular, some examples, such as compounds 6 and 10, shows decreased calculated lipophilicity, when compared to PCP, while retaining moderate activity. Moreover, the germinal aryl amino substituted lactam ring, as exemplified in compounds 7-10 and 11-13, constitutes a novel scaffold with potential application in the design of biologically active compounds.
Application of chemical P450 model systems to studies on drug metabolism. I. Phencyclidine: A multi-functional model substrate
Masumoto,Takeuchi,Ohta,Hirobe
, p. 1788 - 1794 (2007/10/02)
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