79821-69-5

Basic information

• Product Name: N^α-4-toluenesulfonyl-N^α-methylalanine
• Synonyms: N^α-4-toluenesulfonyl-N^α-methylalanine
• CAS NO: 79821-69-5
• Molecular Weight: 257.31
• Mol File: 79821-69-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N^α-4-toluenesulfonyl-N^α-methylalanine(CAS DataBase Reference)
• NIST Chemistry Reference: N^α-4-toluenesulfonyl-N^α-methylalanine(79821-69-5)
• EPA Substance Registry System: N^α-4-toluenesulfonyl-N^α-methylalanine(79821-69-5)

Safety Data

• Hazardous Substances Data: 79821-69-5(Hazardous Substances Data)

Upstream product

• 4816-81-3 p-tosyl-L-alanine 
• 50-00-0 formaldehyd 
• 98-59-9 p-toluenesulfonyl chloride 
• 60522-12-5 (S)-2-(Toluene-4-sulfonylamino)-propionic acid isopropyl ester 
• 60522-13-6 (S)-2-[Methyl-(toluene-4-sulfonyl)-amino]-propionic acid isopropyl ester 

Downstream Products

• 3913-67-5 N-methylalanine 
• 104-15-4 toluene-4-sulfonic acid 

Relevant articles and documents

Access to Optically Pure Benzosultams by Superelectrophilic Activation

Through superacid activation, N-(arenesulfonyl)-aminoalcohols derived from readily available ephedrines or amino acids undergo an intramolecular Friedel-Crafts reaction to afford enantiopure benzosultams bearing two adjacent stereocenters in high yields with fully controlled diastereoselectivity. Low-temperature NMR spectroscopy demonstrated the crucial role played by the conformationally restricted chiral dicationic intermediates.