79834-00-7

Basic information

• Product Name: 2,6-diphenylpyrazolo<1,5-a>pyrimidine
• Synonyms: 2,6-diphenylpyrazolo<1,5-a>pyrimidine
• CAS NO: 79834-00-7
• Molecular Weight: 271.321
• Mol File: 79834-00-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2,6-diphenylpyrazolo<1,5-a>pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-diphenylpyrazolo<1,5-a>pyrimidine(79834-00-7)
• EPA Substance Registry System: 2,6-diphenylpyrazolo<1,5-a>pyrimidine(79834-00-7)

Safety Data

• Hazardous Substances Data: 79834-00-7(Hazardous Substances Data)

Upstream product

• 80234-04-4 2-phenylacrylaldehyde diethyl acetal 
• 1572-10-7 3⁽⁵⁾-phenylpyrazol-5⁽³⁾-amine 
• 827-41-8 3-phenylpyrazol-5-amine 
• 79833-88-8 7-amino-2,6-diphenylpyrazolo<1,5-a>pyrimidine 
• 5841-70-3 phenyl(formyl)acetonitrile 
• 79833-94-6 4,5-dihydro-2,6-diphenylpyrazolo<1,5-a>pyrimidine 

Relevant articles and documents

Oxidative [3+3] Annulation of Atropaldehyde Acetals with 1,3-Bisnucleophiles: An Efficient Method of Constructing Six-Membered Aromatic Rings, Including Salicylates and Carbazoles

An oxidative [3+3] annulation of atropaldehyde acetals with various 1,3-bisnucleophiles was developed using either N-bromosuccinimide or copper(II) bromide as oxidizing reagent and Br?nsted or Lewis acids as catalyst. The [3+3] annulations can be considered mechanistically as oxidizing reagent-induced acid-acid-catalyzed domino reactions established through the concept of auto-tandem catalysis. Alkyl acetoacetates, α-(indol-2-yl)acetate, anilines, 1-methyl-1H-pyrazol-3-amine, ethyl 5-amino-1H-pyrazole-3-carboxylate, and 3-amino-1H-indazole can all be used as 1,3-bisnucleophiles in this type of transformation. The established reactions can very efficiently construct six-membered aromatic rings, including salicylates and carbazoles. A four-step method of synthesizing the anti-inflammatory agent diflunisal was also developed based on the oxidative [3+3] annulation reaction, and the yield was high. (Figure presented.).