79850-99-0Relevant articles and documents
Methoxymethyl-Directed Aryl Metalation. A Total Synthesis of (+/-)-Averufin
Townsend, Craig A.,Davis, Steven G.,Christensen, Siegfried B.,Link, John C.,Lewis, Charles P.
, p. 6885 - 6888 (1981)
A total synthesis of (+/-)-averufin, a central intermediate in aflatoxin biosynthesis, is described.The key steps of the synthesis involve the following: (1) the regiospecific coupling of the phthalide anion of 3b and the benzyne derived in situ from aryl