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799-43-9

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  • (8S,9S,13S,14S,17S)-13-ethyl-17-ethynyl-3-methoxy-4,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-ol

    Cas No: 799-43-9

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799-43-9 Usage

Description

(±)-13-ethyl-3-methoxy-18,19-dinor-17alpha-pregna-2,5(10)-dien-20-yn-17-ol is a synthetic steroid compound derived from the synthesis of Levonorgestrel, an oral contraceptive. It is characterized by its unique molecular structure, featuring a 13-ethyl group, a 3-methoxy group, and the absence of the 18 and 19 carbon atoms in the steroid nucleus. (±)-13-ethyl-3-methoxy-18,19-dinor-17alpha-pregna-2,5(10)-dien-20-yn-17-ol is used as an intermediate in the synthesis of other steroid hormones.

Uses

Used in Pharmaceutical Industry:
(±)-13-ethyl-3-methoxy-18,19-dinor-17alpha-pregna-2,5(10)-dien-20-yn-17-ol is used as a key intermediate in the synthesis of various steroid hormones for pharmaceutical applications. Its unique structure allows for the production of a wide range of steroidal compounds with diverse therapeutic properties, such as contraceptives, anti-inflammatory agents, and hormone replacement therapies.
Used in Contraceptive Development:
As an impurity from the synthesis of Levonorgestrel, (±)-13-ethyl-3-methoxy-18,19-dinor-17alpha-pregna-2,5(10)-dien-20-yn-17-ol plays a role in the development and production of oral contraceptives. Levonorgestrel is a widely used progestin hormone that helps prevent ovulation and fertilization, making it an essential component in birth control pills.
Used in Hormone Replacement Therapy:
(±)-13-ethyl-3-methoxy-18,19-dinor-17alpha-pregna-2,5(10)-dien-20-yn-17-ol is also used as a precursor in the synthesis of hormone replacement therapies. These therapies are designed to alleviate symptoms associated with menopause, such as hot flashes, night sweats, and vaginal dryness, by providing the body with essential hormones.

Check Digit Verification of cas no

The CAS Registry Mumber 799-43-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,9 and 9 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 799-43:
(5*7)+(4*9)+(3*9)+(2*4)+(1*3)=109
109 % 10 = 9
So 799-43-9 is a valid CAS Registry Number.

799-43-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 13-Ethyl-17-ethynyl-3-methoxy-4,6,7,8,9,11,12,13,14,15,16,17-dode cahydro-1H-cyclopenta[a]phenanthren-17-ol (non-preferred name)

1.2 Other means of identification

Product number -
Other names EP Levonorgestrel Impurity B

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:799-43-9 SDS

799-43-9Downstream Products

799-43-9Relevant articles and documents

Preparation method of levonorgestrel

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Paragraph 0025-0026; 0028-0029; 0031-0032, (2020/09/20)

The invention discloses a preparation method of levonorgestrel, and belongs to the technical field of medicine preparation and processing. According to the method, 18-methylestra-2,5(10)-diene-3-methoxy-17-ketone is used as an initial raw material, and the levonorgestrel disclosed by the invention is prepared by virtue of two steps of ethynylation and hydrolysis. According to the preparation method of the levonorgestrel, the defects of a traditional process are overcome and reaction conditions are mild; the method is high in overall conversion rate, easy and convenient to operate, suitable forindustrial production and wide in market prospect.

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