79902-61-7

Basic information

• Product Name: (1S,3S,7R,8R,8aS)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-diethylbutanoate
• CAS NO: 79902-61-7
• Molecular Formula: C₂₇H₄₂O₅
• Molecular Weight: 446.6194
• Mol File: 79902-61-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 585.4°C at 760 mmHg
• Flash Point: 187.5°C
• Density: 1.09g/cm³
• Vapor Pressure: 3.84E-16mmHg at 25°C
• Refractive Index: 1.526
• CAS DataBase Reference: (1S,3S,7R,8R,8aS)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-diethylbutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,3S,7R,8R,8aS)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-diethylbutanoate(79902-61-7)
• EPA Substance Registry System: (1S,3S,7R,8R,8aS)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-diethylbutanoate(79902-61-7)

Safety Data

• Hazardous Substances Data: 79902-61-7(Hazardous Substances Data)

Upstream product

• 35354-15-5 2,2-diethylbutanoyl chloride 
• 813-58-1 triethylacetic acid 
• 79902-57-1 <1S-<1α,3α,7β,8β(2S^*,4S^*)8aβ>>-8-<2-<4-<<(1,1-dimethylethyl)dimethylsilyl>oxy>tetrahydro-6-oxo-2H-pyran-2-yl>ethyl>-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-1-naphthalenyl 2,2-diethylbutanoate 

Relevant articles and documents

3-Hydroxy-3-methylglutaryl-coenzyme A Reductase Inhibitors. 4. Side Chain Ester Derivatives of Mevinolin

Modification of the 2(S)-methylbutyryl moiety of mevinolin led to a series of side chain ester derivatives.A systematic exploration of the structure-activity relationships showed that the introduction of an additional aliphatic group on the carbon α to the carbonyl group increased potency.This obsrevation led to the synthesis of compound 16, which has about 2.5 times the intrinsic inhibitory activity of mevinolin.