799279-10-0

Basic information

• Product Name: Ethanone, 2-hydroxy-2-(4-methylphenyl)-1-phenyl-, (2S)- (9CI)
• Synonyms: Ethanone, 2-hydroxy-2-(4-methylphenyl)-1-phenyl-, (2S)- (9CI)
• CAS NO: 799279-10-0
• Molecular Formula: C15H14O2
• Molecular Weight: 226.27046
• Product Categories: METHYL
• Mol File: 799279-10-0.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethanone, 2-hydroxy-2-(4-methylphenyl)-1-phenyl-, (2S)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-hydroxy-2-(4-methylphenyl)-1-phenyl-, (2S)- (9CI)(799279-10-0)
• EPA Substance Registry System: Ethanone, 2-hydroxy-2-(4-methylphenyl)-1-phenyl-, (2S)- (9CI)(799279-10-0)

Safety Data

• Hazardous Substances Data: 799279-10-0(Hazardous Substances Data)

Upstream product

• 134-84-9 4-Methylbenzophenone 
• 68-12-2 N,N-dimethyl-formamide 
• 76176-06-2 2-hydroxy-2-phenyl-2-(p-tolyl)acetaldehyde 
• 799279-06-4 (2R,3S)-2-phenyl-2-hydroxy-3-(4-methylphenyl)-3-(2-methoxyethoxymethoxy)propanoic acid 
• 799279-03-1 (2S,5R,1'S)-2-(tert-butyl)-5-phenyl-5-[1'-(4-methylphenyl)-1'-(2-methoxyethoxymethoxy)methyl]-1,3-dioxolan-4-one 
• 799279-00-8 (2S,5R,1'S)-2-(tert-butyl)-5-phenyl-5-[1'-hydroxy-1'-(4-methylphenyl)methyl]-1,3-dioxolan-4-one 
• 104-87-0 4-methyl-benzaldehyde 
• 81036-97-7 (2S,5S)-2-tert-butyl-5-phenyl-1,3-dioxolan-4-one 
• 611-71-2 (R)-Mandelic Acid 
• 799279-08-6 (2S)-1-phenyl-2-(4-methylphenyl)-2-(2-methoxyethoxymethoxy)ethanone 
• 2431-00-7 p-methylbenzil 
• 106-38-7 para-bromotoluene 
• 582-24-1 1-phenyl-2-hydroxyethanone 
• 2431-23-4 4-methylbenzoin 

Downstream Products

• 2431-23-4 4-methylbenzoin 
• 74614-35-0 α-methoxy-4'-methyl-deoxybenzoin oxime 

Relevant articles and documents

Enantioselective Acyloin Rearrangement of Acyclic Aldehydes Catalyzed by Chiral Oxazaborolidinium Ion

A catalytic enantioselective acyloin rearrangement of acyclic aldehydes to synthesize highly optically active acyloin derivatives is described. In the presence of a chiral oxazaborolidinium ion catalyst, the reaction provided chiral α-hydroxy aryl ketones in high yield (up to 95%) and enantioselectivity (up to 98% ee). In addition, the enantioselective acyloin rearrangement of α,α-dialkyl-α-siloxy aldehydes produced chiral α-siloxy alkyl ketones in high yield (up to 92%) with good enantioselectivity (up to 89% ee).

Green preparation method α - hydroxyketone

The invention relates to a green preparation method of alpha-hydroxyketone. The method comprises the following steps: adding ketone, iodine, 1,4-diazabicyclo[2.2.2]octane and methanol into a glass reaction bottle in sequence; then stirring and reacting for 14 to 30h at room temperature in an air atmosphere under the irradiation of a 23W compact type fluorescent lamp, so as to obtain a reaction mixture; carrying out silica gel column chromatographic separation to obtain the pure alpha-hydroxyketone. The green preparation method provided by the invention has the characteristics of greenness, high efficiency, simplicity in operation, moderate conditions, wide applicability and easiness for industrialization.

(S)-Mandelic acid enolate as a chiral benzoyl anion equivalent for the enantioselective synthesis of non-symmetrically substituted benzoins

A strategy for the enantioselective synthesis of non-symmetrically substituted benzoins from (S)-mandelic acid and aromatic aldehydes has been developed. This strategy is based on a diastereoselective aldol reaction of the lithium enolate of the 1,3-dioxo