79929-43-4Relevant articles and documents
Synthesis of n-alkyl terminal halohydrin esters from acid halides and cyclic ethers or thioethers under solvent- and catalyst-free conditions
Venkatesham, Kunuru,Chanti Babu, Dokuburra,Bharadwaj, Tatipamula Vinay,Bunce, Richard A.,Rao, Chitturi Bhujanga,Venkateswarlu, Yenamandra
, p. 51991 - 51994 (2014)
An efficient and eco-friendly protocol has been developed for the preparation of n-alkyl terminal halohydrin esters under solvent- and catalyst-free conditions. Ring opening of cyclic ethers by organic acid halides affords the 1,4- and 1,5-halohydrins, OH-protected by different acyl groups. The green reaction conditions, simple work-up procedures, high yields and broad substrate scope of the reaction highlight the positive features of this method. This journal is
