79965-62-1 Usage
Description
4-Methyl-3-nitroquinoline, with the molecular formula C10H7N3O2, is a yellow crystalline solid that possesses a molecular weight of 197.18 g/mol. This chemical compound is primarily recognized for its role as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Additionally, it has garnered interest for its potential application as a fluorescent probe for detecting metal ions. However, it is essential to note that 4-Methyl-3-nitroquinoline exhibits mutagenic and cytotoxic properties, which have led to ongoing research into its health and environmental implications.
Uses
Used in Pharmaceutical and Agrochemical Industries:
4-Methyl-3-nitroquinoline is utilized as a crucial intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its unique chemical structure allows it to serve as a building block for the development of new drugs and agricultural products, contributing to advancements in these fields.
Used in Research and Development:
As a fluorescent probe, 4-Methyl-3-nitroquinoline is employed in the detection of metal ions. This application is particularly valuable in research settings, where the identification and analysis of metal ions are essential for understanding chemical reactions and developing new technologies.
Used in Environmental and Health Impact Studies:
Due to its mutagenic and cytotoxic effects, 4-Methyl-3-nitroquinoline is the subject of research aimed at understanding its potential health and environmental impacts. This research is vital for assessing the risks associated with the compound and informing the development of safety guidelines and regulations.
Check Digit Verification of cas no
The CAS Registry Mumber 79965-62-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,9,6 and 5 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 79965-62:
(7*7)+(6*9)+(5*9)+(4*6)+(3*5)+(2*6)+(1*2)=201
201 % 10 = 1
So 79965-62-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H8N2O2/c1-7-8-4-2-3-5-9(8)11-6-10(7)12(13)14/h2-6H,1H3
79965-62-1Relevant articles and documents
Alkylation of Nitropyridines via Vicarious Nucleophilic Substitution
Antoniak, Damian,Barbasiewicz, Micha?
supporting information, p. 516 - 519 (2022/01/20)
Electrophilic nitropyridines react with sulfonyl-stabilized carbanions to give products of C-H alkylation via vicarious nucleophilic substitution. The process consists of formation of the Meisenheimer-type adduct followed by base-induced β-elimination of the sulfinic acid (e.g., PhSO2H). Mechanistic studies reveal that in the latter step alkyl substituent and adjacent nitro group tend to planarize for effective stabilization of benzyl anion, and thus, adduct of hindered isopropyl carbanion remains stable toward elimination for steric reasons.
Naphthyridines. IV. Synthesis of Benzo-1,7-naphthyridines
Baumgarten, Henry E.,Barkley, Raymond P.,Chiu, Shuet-Hing Lee,Thompson, Robert D.
, p. 925 - 928 (2007/10/02)
Benzo-1,7-naphthyridines have been synthesized from 3-nitrolepidine (3) by a sequence involving monobromination of the methyl group of 3, oxidation of the bromomethyl group to the carboxyaldehyde group by Franzen's trimethylamine N-oxide procedure, and
