8001-28-3

Basic information

• Product Name: CROTON OIL
• Synonyms: crotontigliuml.oil;oils,croton;oleumtiglii;CROTON OIL;Ncgc00091568-01;Croton tiglia seed oil;Croton tiglium seed oil;Fats and Glyceridic oils, croton
• CAS NO: 8001-28-3
• Molecular Formula: Unspecified
• Molecular Weight: 0
• EINECS: 310-127-6
• Product Categories: Pharmaceutical Intermediates;Biochemicals and Reagents;Lipids;Oils
• Mol File: 8001-28-3.mol
• Article Data: 0

Chemical Properties

• Flash Point: 74 °C
• Appearance: Pale Yellow to Brown/Oil
• Density: 0.94 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.477
• Water Solubility: Soluble in alcohol, chloroform, ether, and petroleum ether. Insoluble in water.
• Merck: 14,2598
• CAS DataBase Reference: CROTON OIL(CAS DataBase Reference)
• NIST Chemistry Reference: CROTON OIL(8001-28-3)
• EPA Substance Registry System: CROTON OIL(8001-28-3)

Safety Data

• Safety Statements: 23-24/25
• RIDADR: 2810
• WGK Germany: 3
• RTECS: GQ6300000
• TSCA: Yes
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 8001-28-3(Hazardous Substances Data)

Usage

Description

CROTON OIL is a natural extract derived from the seeds of the Croton tiglium plant, rich in phorbol, phorbol esters, and glycerides of saturated fatty acids. It has been traditionally used for its medicinal properties and is known for its ability to induce acute skin inflammation.

Uses

Used in Dermatology:
CROTON OIL is used as an active ingredient in phenol-based facial peels for its skin rejuvenating properties. Dermatologists, plastic surgeons, and other practitioners can adjust the concentration of croton oil in the peel to customize the treatment for specific patients or skin areas, such as the neck or around the eyes.
Used in Traditional Medicine:
CROTON OIL is used as a counterirritant and cathartic in medicine, applied directly to the skin for muscle and joint pain relief.
Used in Lamps and Soap Production:
In Malaysia, CROTON OIL is utilized in lamps and soap-making, highlighting its versatility in various applications.
Used in Skin Inflammation Induction:
CROTON OIL has been employed to induce acute skin inflammation for specific therapeutic purposes.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

OILS, MISCELLANEOUS: CROTON react with acids to liberate heat. Heat is also generated by interaction with caustic solutions. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Flammable hydrogen is generated by mixing with alkali metals and hydrides.

Hazard

Strong skin irritant, ingestion of small amounts may be fatal.

Fire Hazard

CROTON OIL is probably combustible.