80058-84-0

Basic information

• Product Name: 4-BROMO-2,6-BIS(1-METHYLETHYL)BENZENAMINE
• Synonyms: 4-BROMO-2,6-BIS(1-METHYLETHYL)BENZENAMINE;4-broMo-2,6-bis(propan-2-yl)aniline;4-BroMo-2,6-diisopropylaniline;Benzenamine,4-bromo-2,6-bis(1-methylethyl)-;4-bromo-2,6-diisopropylbenzenamine;4-Bromo-2,6-diisopropyl-phenylamine;4-BROMO-2,6-BIS(1-METHYLETHYL)BENZEMINE;2,6-diisopropyl-4-bromoaniline
• CAS NO: 80058-84-0
• Molecular Formula: C₁₂H₁₈BrN
• Molecular Weight: 256.18200
• Mol File: 80058-84-0.mol
• Article Data: 44

Chemical Properties

• Boiling Point: 300.513 °C
• Flash Point: 135.546 °C
• Appearance: /
• Density: 1.231 g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.553
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 3.54±0.10(Predicted)
• CAS DataBase Reference: 4-BROMO-2,6-BIS(1-METHYLETHYL)BENZENAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-2,6-BIS(1-METHYLETHYL)BENZENAMINE(80058-84-0)
• EPA Substance Registry System: 4-BROMO-2,6-BIS(1-METHYLETHYL)BENZENAMINE(80058-84-0)

Safety Data

• Hazardous Substances Data: 80058-84-0(Hazardous Substances Data)

Usage

Description

4-BROMO-2,6-BIS(1-METHYLETHYL)BENZENAMINE, also known as 4-Bromo-2,6-diisopropylaniline, is an organic compound characterized by the presence of a bromine atom at the 4-position and two isopropyl groups attached to the 2,6-positions of a benzene ring. It exhibits chemical properties that make it a versatile building block in various chemical reactions and synthesis processes.

Uses

Used in Chemical Synthesis:
4-BROMO-2,6-BIS(1-METHYLETHYL)BENZENAMINE is used as a reactant in the preparation of hyperbranched ethylene oligomers. Its unique structure allows it to participate in various chemical reactions, contributing to the formation of complex and highly branched polymeric structures with potential applications in diverse fields.
Used in Polymer Industry:
In the polymer industry, 4-BROMO-2,6-BIS(1-METHYLETHYL)BENZENAMINE is used as a monomer for the synthesis of specialty polymers. Its bromine atom and isopropyl groups can be utilized to create polymers with specific properties, such as enhanced thermal stability, mechanical strength, or chemical resistance, depending on the desired application.
Used in Pharmaceutical Industry:
4-BROMO-2,6-BIS(1-METHYLETHYL)BENZENAMINE may also find use in the pharmaceutical industry as an intermediate in the synthesis of various drug molecules. Its chemical reactivity and structural features can be leveraged to create new compounds with potential therapeutic applications.
Used in Research and Development:
In research and development settings, 4-BROMO-2,6-BIS(1-METHYLETHYL)BENZENAMINE serves as a valuable compound for exploring new chemical reactions and developing innovative synthetic methods. Its unique properties can be studied to gain insights into the underlying mechanisms of various chemical processes, ultimately contributing to the advancement of scientific knowledge in the field of organic chemistry.

InChI:InChI=1/C12H18BrN/c1-7(2)10-5-9(13)6-11(8(3)4)12(10)14/h5-8H,14H2,1-4H3

Upstream product

• 50522-40-2 2,6-diisopropylaniline hydrochloric acid salt 
• 24544-04-5 2,6-diisopropylbenzenamine 

Downstream Products

• 70630-25-0 2-[(4-Bromo-2,6-diisopropyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid methyl ester 
• 949079-50-9 C₃₈H₃₆O₄N₂Br₂ 
• 80058-85-1 2,6-diisopropyl-4-phenoxyaniline 
• 946147-63-3 5-bromo-2-iodo-1,3-diisopropylbenzene 
• 1270006-62-6 N-(2,6-diisopropyl-4-(pyren-1-ylethynyl)phenyl)formamide 
• 1270006-61-5 1-((4-isocyano-3,5-diisopropylphenyl)ethynyl)pyrene 
• 220721-02-8 3,5-diisopropyl-4-formamido-1-trimethylsilylethynylbenzene 
• 220721-05-1 5-ethynyl-2-isocyano-1,3-diisopropylbenzene 
• 220721-32-4 2,6-diisopropyl-4-bromo-1-isocyanobenzene 
• 220721-30-2 2,6-diisopropyl-4-bromo-1-formamidobenzene 

Relevant articles and documents

New Bromine-Containing Bis(arylimino)acenaphthenes and Related Metal Complexes

Abstract: The condensation reactions of 5-bromoacenaphthenequinone with 2,6-diisopropylaniline and 4?bromo-2,6-di-iso-propylaniline afford new mono- and tribromosubstituted bis(arylimino)acenaphthenes: 1,2-bis[(2,6-diisopropylphenyl)imino]-5-bromacenaphthene (Dpp-Br-Bian) (L1) and 1,2-bis[(4-bromo-2,6-diisopropylphenyl)imino]-5-bromacenaphthene (p-Br-Dpp-Br-Bian) (L2), respectively. Compounds L1 and L2 act as neutral ligands in the [(Dpp-Br-Bian)ZnCl2] (I), [(p-Br-Dpp-Br-Bian)AlCl3] (III), and [(p-Br-Dpp-Br-Bian)GaCl3] (IV) complexes synthesized by the reactions of free diimines with the corresponding metal chlorides. The reaction of the known dibromosubstituted derivative 1,2-bis[(4-bromo-2,6-di-iso-propylphenyl)iminoacenaphthene (p-Br-Dpp-Bian) (L3) with copper(I) chloride also affords complex [(p-Br-Dpp-Bian)CuCl] (II) with the neutral diimine ligand. New compounds L1, L2, and I–IV are characterized by NMR, IR spectroscopy, and elemental analysis. The molecular structure of complex I is determined by X-ray structure analysis.

Synthesis method of diafenthiuron impurities A and B

The invention provides a preparation method of the diafenthiuron impurities A and B. 2, 6-isopropylaniline, phenol, triphosgene, tert-butylamine and tert-butyl formamidine hydrochloride are used as raw materials, a material basis is provided for normatively researching the impurities, and the method can also be used for qualitative and quantitative analysis of the impurities in diafenthiuron production. And the impurities are controlled within a safe and reasonable limit range, so that the quality standard of the diafenthiuron can be improved, and important guiding significance is provided for safe medication of the masses.

Development of effective bidentate diphosphine ligands of ruthenium catalysts toward practical hydrogenation of carboxylic acids

Hydrogenation of carboxylic acids (CAs) to alcohols represents one of the most ideal reduction methods for utilizing abundant CAs as alternative carbon and energy sources. However, systematic studies on the effects of metal-to-ligand relationships on the catalytic activity of metal complex catalysts are scarce. We previously demonstrated a rational methodology for CA hydrogenation, in which CA-derived cationic metal carboxylate [(PP)M(OCOR)]+ (M = Ru and Re; P = one P coordination) served as the catalyst prototype for CA self-induced CA hydrogenation. Herein, we report systematic trial- and-error studies on how we could achieve higher catalytic activity by modifying the structure of bidentate diphosphine (PP) ligands of molecular Ru catalysts. Carbon chains connecting two P atoms as well as Ar groups substituted on the P atoms of PP ligands were intensively varied, and the induction of active Ru catalysts from precatalyst Ru(acac)3 was surveyed extensively. As a result, the activity and durability of the (PP)Ru catalyst substantially increased compared to those of other molecular Ru catalyst systems, including our original Ru catalysts. The results validate our approach for improving the catalyst performance, which would benefit further advancement of CA self-induced CA hydrogenation.