80096-44-2Relevant articles and documents
Synthesis, antimicrobial, and anti-inflammatory activities of acetamido pyrrolyl azoles
Sowmya, Donthamsetty V.,Basha, Shaik Sharafuddin,Devi, Palampalli Uma Maheswari,Lavanyalatha, Yerraguravagari,Padmaja, Adivireddy,Padmavathi, Venkatapuram
, p. 1010 - 1021 (2017/04/13)
The acetamido pyrrolyl oxazoles/thiazoles/imidazoles were prepared and tested for their antimicrobial and anti-inflammatory activities. The nitro substituted acetamido pyrrolyl thiazole (11f) and pyrrolyl imidazole (12f) exhibited promising antibacterial activity against K. pneumoniae. The compound 12f showed good antifungal activity against P. chrysogenum. The methoxy acetamido pyrrolyl oxazole (10c) displayed potential anti-inflammatory activity.
Synthesis and structure-activity relationships of aroylpyrrole alkylamide bradykinin (B2) antagonists
Youngman, Mark A.,Carson, John R.,Lee, Jung S.,Dax, Scott L.,Zhang, Sui-Po,Colburn, Ray W.,Stone, Dennis J.,Codd, Ellen E.,Jetter, Michele C.
, p. 1341 - 1344 (2007/10/03)
The synthesis and structure-activity relationships of a novel series of aroylpyrrole alkylamides as potent selective bradykinin B2 receptor antagonists are described. Several members of this series display nanomolar affinity at the B2 receptor and show activity in an animal model of antinociception.
Aroyl-substituted pyrroles
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, (2008/06/13)
The compounds are of the class of 5-aroyl-pyrrole alkanoic acids and corresponding acid derivatives thereof useful as anti-inflammatory agents and as synthetic intermediates.
