80141-51-1 Usage
Description
(R)-3-CHLORO-2-METHYLPROPIONYL CHLORIDE, with the molecular formula C4H6Cl2O, is a chemical compound that is colorless to light yellow in appearance and has a pungent odor. It is highly reactive and corrosive, necessitating careful handling and the use of personal protective equipment to prevent skin and respiratory irritation. (R)-3-CHLORO-2-METHYLPROPIONYL CHLORIDE is typically stored in a cool, dry place to maintain its stability.
Uses
Used in Chemical Research and Synthesis:
(R)-3-CHLORO-2-METHYLPROPIONYL CHLORIDE is used as a reagent in chemical research and synthesis processes for the introduction of the (R)-3-chloro-2-methylpropionyl group into organic molecules. Its high reactivity makes it a valuable tool in the creation of various organic compounds, contributing to the advancement of chemical research and the development of new materials and products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (R)-3-CHLORO-2-METHYLPROPIONYL CHLORIDE is used as an intermediate in the synthesis of various drugs and pharmaceutical compounds. Its ability to introduce a specific functional group into organic molecules aids in the development of new medications and therapies.
Used in Chemical Synthesis for Specialized Applications:
(R)-3-CHLORO-2-METHYLPROPIONYL CHLORIDE is also used in the synthesis of compounds for specialized applications, such as agrochemicals, dyes, and other industrial chemicals. Its versatility in introducing the (R)-3-chloro-2-methylpropionyl group into organic molecules makes it a valuable asset in the development of these products.
Check Digit Verification of cas no
The CAS Registry Mumber 80141-51-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,1,4 and 1 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 80141-51:
(7*8)+(6*0)+(5*1)+(4*4)+(3*1)+(2*5)+(1*1)=91
91 % 10 = 1
So 80141-51-1 is a valid CAS Registry Number.
80141-51-1Relevant articles and documents
Chemoenzymatic Synthesis in Flow Reactors: A Rapid and Convenient Preparation of Captopril
De Vitis, Valerio,Dall'Oglio, Federica,Pinto, Andrea,De Micheli, Carlo,Molinari, Francesco,Conti, Paola,Romano, Diego,Tamborini, Lucia
, p. 668 - 673 (2017/09/06)
The chemoenzymatic flow synthesis of enantiomerically pure captopril, a widely used antihypertensive drug, is accomplished starting from simple, inexpensive, and readily available reagents. The first step is a heterogeneous biocatalyzed regio- and stereoselective oxidation of cheap prochiral 2-methyl-1,3-propandiol, performed in flow using immobilized whole cells of Acetobacter aceti MIM 2000/28, thus avoiding the use of aggressive and environmentally harmful chemical oxidants. The isolation of the highly hydrophilic intermediate (R)-3-hydroxy-2-methylpropanoic acid is achieved in-line by using a catch-and-release strategy. Then, three sequential high-throughput chemical steps lead to the isolation of captopril in only 75 min. In-line quenching and liquid–liquid separation enable breaks in the workflow and other manipulations to be avoided.
Development of the conditions of synthesis of p-chlorophenyl methacrylate of the desired purity grade
Kobyakova,Kuz'Mina,Beshenova,Beloded
experimental part, p. 123 - 127 (2009/09/06)
The process of synthesis of p-chlorophenyl methacrylate by the reaction of p-chlorophenol with methacryloyl chloride was developed, identification and quantitative determination of admixtures in the targeted compound was carried out. The optimal conditions of the synthesis for obtaining the high quality monomer were developed.
Synthesis of captopril starting from an optically active β-hydroxy acid
Shimazaki,Hasegawa,Kan,et al.
, p. 3139 - 3146 (2007/10/02)
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