80288-49-9 Usage
Description
3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE, also known as Furafylline, is a chemical compound with a unique structure that features a furanylmethyl group attached to a purine-based core. 3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE is characterized by its ability to selectively inhibit certain biological processes, making it a valuable tool in various applications.
Uses
Used in Pharmaceutical Industry:
Furafylline is used as a selective inhibitor of human cytochrome P450, an enzyme family that plays a crucial role in the metabolism of drugs and other substances in the body. Its inhibitory action is valuable for studying the role of cytochrome P450 in drug metabolism and for developing drugs with reduced drug-drug interactions.
Used in Research Applications:
Furafylline is also reported to inhibit the oxidation of caffeine, which is an important aspect of research in pharmacology and toxicology. By inhibiting caffeine oxidation, Furafylline can help researchers understand the metabolic pathways involved in caffeine metabolism and potentially identify new targets for drug development.
Biochem/physiol Actions
Furafylline (1,8-dimethyl-3-(2′ -furfuryl)methylxanthine) is a xanthine derivative. It is preferred in treating asthma. It serves as a N3-demethylation inhibitor of caffeine. Furafylline does not show much effect on human monooxygenase activities. It is considered as an efficient bronchodilator and as an inhibitor of anaphylactic reactions, when compared to theophylline.
Check Digit Verification of cas no
The CAS Registry Mumber 80288-49-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,2,8 and 8 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 80288-49:
(7*8)+(6*0)+(5*2)+(4*8)+(3*8)+(2*4)+(1*9)=139
139 % 10 = 9
So 80288-49-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H12N4O3/c1-2-7-19-10-5-3-9(4-6-10)12-13-15-16(14-12)8-11(17)18/h2-6H,1,7-8H2,(H,17,18)
