802909-30-4Relevant articles and documents
Use of N-N bond stereodynamics in ring-closing metathesis to form medium-sized rings and macrocycles
Yi, Jin Kim,Lee, Daesung
, p. 4351 - 4353 (2007/10/03)
(Chemical Equation Presented) A unique strategy based on double ring-closing metathesis for the formation of a 14-membered macrocyclic enamide has been developed. This strategy hinges upon the well-known stereodynamic and conformational behavior of N-substituted diacylhydrazines, which promotes an effective ring-closing metathesis of hydrazine-derived dienes and enynes to form 8- to 14-membered rings.