80295-33-6

Basic information

• Product Name: C1Q, HUMAN
• Synonyms: C1Q, HUMAN;COMPLEMENT COMPONENT C1Q;COMPLEMENT C1Q, HUMAN;COMPLEMENT C1Q PROTEIN;COMPLEMENT C1Q PROTEIN HUMAN;COMPLEMENT 1Q, HUMAN;COMPLEMENT COMPONENT C1Q FROM HUMAN*SERUM;activity:18-30units/mgproteinsalt-free,lyophilizedsolidbysds
• CAS NO: 80295-33-6
• Molecular Weight: 0
• Mol File: 80295-33-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /solution ( 10 mM HEPES, pH 7.2. and 0.3 M NaCl )
• Storage Temp.: −20°C
• CAS DataBase Reference: C1Q, HUMAN(CAS DataBase Reference)
• NIST Chemistry Reference: C1Q, HUMAN(80295-33-6)
• EPA Substance Registry System: C1Q, HUMAN(80295-33-6)

Safety Data

• Hazard Codes: B
• WGK Germany: 3
• Hazardous Substances Data: 80295-33-6(Hazardous Substances Data)

Usage

Description

C1Q, HUMAN, also known as Complement component C1q, is a crucial protein involved in the innate immune system. It is a key regulator of platelet activation and plays a significant role in inflammatory conditions such as coronary heart disease. C1Q, HUMAN has the ability to inhibit collagen-induced aggregation and enhance the production of reactive oxygen species (ROS), making it a vital component in the body's defense mechanisms.

Uses

Used in Medical Research:
C1Q, HUMAN is used as a research subject for understanding its role in platelet activation and its impact on inflammatory conditions such as coronary heart disease. Its ability to inhibit collagen-induced aggregation and enhance ROS production makes it a valuable tool for studying the underlying mechanisms of these conditions.
Used in Drug Development:
C1Q, HUMAN is used as a target for drug development to modulate its activity and potentially treat inflammatory conditions. By targeting C1Q, HUMAN, researchers can develop therapies that regulate platelet activation and ROS production, potentially leading to new treatments for coronary heart disease and other related conditions.
Used in Diagnostics:
C1Q, HUMAN can be used as a biomarker for diagnosing inflammatory conditions. Its involvement in platelet activation and ROS production makes it a potential indicator of the presence and severity of these conditions. By measuring C1Q, HUMAN levels, healthcare professionals can gain insights into a patient's inflammatory status and make informed decisions regarding treatment options.

Biochem/physiol Actions

≥150,000 C1qH50 units/mg and ≥70% C1q activity in normal human serum on a mg/mg basis