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80308-80-1

80308-80-1

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80308-80-1 Usage

General Description

4-Bromo-1-vinyl-1H-pyrazole is a chemical compound with the molecular formula C6H5BrN2. It is a pyrazole derivative with a bromine atom and a vinyl group attached to the pyrazole ring. 4-BROMO-1-VINYL-1H-PYRAZOLE is used in organic synthesis as a building block for the preparation of various pharmaceuticals and agrochemicals. Its unique structure and reactivity make it a versatile intermediate in the production of complex molecules. Additionally, 4-Bromo-1-vinyl-1H-pyrazole has been studied for its potential biological activities and medicinal properties, showing promise in applications such as anticancer and antiviral drugs.

Check Digit Verification of cas no

The CAS Registry Mumber 80308-80-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,3,0 and 8 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 80308-80:
(7*8)+(6*0)+(5*3)+(4*0)+(3*8)+(2*8)+(1*0)=111
111 % 10 = 1
So 80308-80-1 is a valid CAS Registry Number.
InChI:InChI=1/C5H5BrN2/c1-2-8-4-5(6)3-7-8/h2-4H,1H2

80308-80-1Downstream Products

80308-80-1Relevant articles and documents

Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors

Acton, John J.,Adpressa, Donovon,Ardolino, Michael J.,Bennett, David Jonathan,Chau, Ryan W.,Ciaccio, Paul J.,Dimauro, Erin F.,Faltus, Robert,Fell, Matthew J.,Fuller, Peter H.,Gulati, Anmol,Hegde, Laxminarayan G.,Johnson, Rebecca E.,Kattar, Solomon D.,Kennedy, Matthew E.,Keylor, Mitchell H.,Lesburg, Charles A.,Lin, Shishi,Liu, Ping,Margrey, Kaila A.,McMinn, Spencer E.,Morriello, Gregori J.,Neelamkavil, Santhosh,Nogle, Lisa,Otte, Karin M.,Palte, Rachel L.,Piesvaux, Jennifer,Pio, Barbara,Poremba, Kelsey E.,Simov, Vladimir,Su, Jing,Wood, Harold B.,Woodhouse, Janice D.,Xiong, Tina,Yan, Xin,Zarate, Cayetana

, p. 838 - 856 (2022/01/20)

The leucine-rich repeat kinase 2 (LRRK2) protein has been genetically and functionally linked to Parkinson's disease (PD), a disabling and progressive neurodegenerative disorder whose current therapies are limited in scope and efficacy. In this report, we

The N-vinyl group as a protection group of the preparation of 3(5)-substituted pyrazoles via bromine-lithium exchange

Iddon, Brian,T?nder, Janne Ejrn?s,Hosseini, Masood,Begtrup, Mikael

, p. 56 - 61 (2007/10/03)

Treatment of 3,4,5-tribromopyrazole with 1,2-dibromoethane and triethylamine gave 3,4,5-tribromo-1-vinylpyrazole, which underwent regioselective bromine-lithium exchange at the 5-position. Subsequent addition of an electrophile gave 5-substituted 3,4-dibr

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