80311-94-0

Basic information

• Product Name: Acetamide, N-[(2-hydroxyphenyl)methyl]-
• CAS NO: 80311-94-0
• Molecular Formula: C9H11NO2
• Molecular Weight: 165.192
• Mol File: 80311-94-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Acetamide, N-[(2-hydroxyphenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-[(2-hydroxyphenyl)methyl]-(80311-94-0)
• EPA Substance Registry System: Acetamide, N-[(2-hydroxyphenyl)methyl]-(80311-94-0)

Safety Data

• Hazardous Substances Data: 80311-94-0(Hazardous Substances Data)

Upstream product

• 91133-29-8 1-acetoxy-2-(acetylamino-methyl)-benzene 
• 932-30-9 2-Hydroxybenzylamine 
• 108-24-7 acetic anhydride 
• 63452-53-9 N-acetyl-2-methoxybenzylamine 
• 6850-57-3 2-methoxybenzylamine 
• 588-46-5 N-(phenylmethyl)acetamide 
• 85690-51-3 N-(2-aminobenzyl)acetamide 
• 3852-14-0 N,N-methylenediacetamide 
• 108-95-2 phenol 
• 90-02-8 salicylaldehyde 
• 21013-96-7 (E)-2-hydroxylbenzaldehyde oxime 

Downstream Products

• 1448992-66-2 tert-butyl-3-(2-(aminomethyl)phenoxy)propylcarbamate 
• 1448992-68-4 [3-(2-isocyanatomethyl-phenoxy)-propyl]-carbamic acid tert-butyl ester 
• 1448992-67-3 [ (2-{3-[2-(3-tert-butoxycarbonylamino-propoxy)-benzyl]-ureido}thiazole-4-carbonyl)-amino]-acetic acid methyl ester 
• 1448992-69-5 [(2-{3-[2-(3-tert-butoxycarbonylamino-propoxy)-benzyl ]-ureido}-thiazole-4-carbonyl)-amino ]-acetic acid 
• 1448992-70-8 methyl-3-(2-(2-(3-(2-(3-(tert-butoxycarbonylamino)propoxy) benzyl)ureido )thiazole-4-carboxamido )acetamido )-3-phenylpropanoate 
• 1448992-73-1 (R)-ethyl-3-(2-(2-(3-(2-(3-(tert-butoxycarbonylamino)propoxy)benzyl)ureido)thiazole-4-carboxamido)acetamido)-3-(pyridin-3-yl)propanoate 
• 1448992-65-1 {3-[2-(acetylamino-methyl)-phenoxy]-propyl}-carbamic acid tert-butyl ester 
• 852951-41-8 N-{2-[(2S)-oxiran-2-ylmethoxy]benzyl}acetamide 
• 1027204-48-3 4-[2-(acetylamino-methyl)-phenoxy]-butyric acid 
• 1026870-07-4 4-[2-(acetylamino-methyl)-phenoxy]-butyric acid ethyl ester 

Relevant articles and documents

INTEGRIN ANTAGONIST CONJUGATES FOR TARGETED DELIVERY TO CELLS EXPRESSING ALPHA-V-BETA-3

The invention relates to compounds of formula (I): wherein R1, R2, and n are defined in the detailed description and claims. In particular, the present invention relates to the compounds of formula (I) for use in the manufacture and delivery of conjugated moieties such as small molecules, peptides, nucleic acids, fluorescent moieties, and polymers which are linked to alpha-V-beta-3 integrin antagonists to target cells expressing alpha-V-beta-3.

NOVEL COMPOUNDS

The invention provides compounds of formula (I) wherein m, R1, n, R2, q, X, Y, Z, t, R3, R4, R5, R6, R7 and R8 are as defined in the specification, processes for their

AROMATIC HYDROXYLATION OF BENZYLAMIDES BY POTASSIUM SUPEROXIDE

N-benzylamides react with potassium superoxide in benzene in presence of 18-crown-6 ether to give ortho and para hydroxylated products.A mechanism is proposed for this reaction, involving the nucleophilic attack of superoxide anion to amide carbonyl and hydrogen abstraction from benzyle methylene by the substrate-superoxide adduct.