80448-02-8

Basic information

• Product Name: Phenol, 4-(phenylseleno)-
• CAS NO: 80448-02-8
• Molecular Formula: C12H10OSe
• Molecular Weight: 249.171
• Mol File: 80448-02-8.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: Phenol, 4-(phenylseleno)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-(phenylseleno)-(80448-02-8)
• EPA Substance Registry System: Phenol, 4-(phenylseleno)-(80448-02-8)

Safety Data

• Hazardous Substances Data: 80448-02-8(Hazardous Substances Data)

Upstream product

• 540-38-5 p-Iodophenol 
• 41924-21-4 phenyl tributylstannyl selenide 
• 1666-13-3 diphenyl diselenide 
• 108-95-2 phenol 
• 23974-72-3 sodium phenylselenide 
• 33527-94-5 4-acetoxyiodobenzene 
• 71597-85-8 (p-hydroxyphenyl)boronic acid 
• 106-41-2 4-bromo-phenol 
• 6996-92-5 benzeneseleninic acid 
• 80447-92-3 (phenylseleno)dimethylsulfonium tetrafluoroborate 
• 5707-04-0 Phenylselenyl chloride 
• 19089-85-1 p-diazophenol 
• 10467-10-4 ethylmagnesium iodide 
• 80448-01-7 p-methoxyphenyl phenyl selenide 

Relevant articles and documents

Selective estrogen receptor modulator compounds containing phenylselenyl and application of compounds in anti-breast cancer drugs

The present invention discloses selective estrogen receptor modulator compounds containing phenylselenyl and an application of the compounds in anti-breast cancer drugs. According to the compounds provided by the present invention, 3-(4-hydroxyphenyl)-4-(

Efficient heterogeneous copper-catalysed C–Se coupling of aryl iodides with symmetrical diselenides towards unsymmetrical monoselenides

A highly efficient heterogeneous copper(I)-catalysed C–Se coupling of aryl iodides with diaryl diselenides was achieved in dimethylformamide at 110 °C under neutral conditions by using a 10 mol% of bipyridine-functionalised MCM-41-supported copper(I) complex [bpy-MCM-41-CuI] as the catalyst and magnesium as the reductive reagent, yielding a variety of unsymmetrical diaryl selenides in good to excellent yields. This heterogeneous copper catalyst can be easily recovered by a simple filtration of the reaction solution and recycled at least seven times without significant loss of activity.

A convenient and efficient copper-catalyzed synthesis of unsymmetrical and symmetrical diaryl chalcogenides from arylboronic acids in ethanol at room temperature

A simple and convenient approach for the synthesis of unsymmetrical diaryl chalcogenides (Te, Se, and S) has been developed by copper-catalyzed cross-coupling reaction of organoboronic acid with diaryl dichalcogenide in ethanol using NaBH4 in air or oxygen. The present methodology is highly practical for the synthesis of unsymmetrical diaryl tellurides with various functionalities such as -NO2, -F, -Br, and -COOH that have been obtained in good to excellent yields. Methodology is also effective for the synthesis of unsymmetrical diaryl selenides and sulfides. Moreover, symmetrical diaryl selenides have also been obtained from arylboronic acids using elemental selenium powder under optimized reaction conditions. The use of NaBH 4 is the key for the development of milder reaction conditions, which enable the construction of unsymmetrical diaryl chalcogenides from boronic acid substrates in ethanol at room temperature.