80472-59-9

Basic information

• Product Name: Benzenesulfonothioic acid, 4-methyl-, S-(4-methoxyphenyl) ester
• CAS NO: 80472-59-9
• Molecular Formula: C14H14O3S2
• Molecular Weight: 294.395
• Mol File: 80472-59-9.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: Benzenesulfonothioic acid, 4-methyl-, S-(4-methoxyphenyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonothioic acid, 4-methyl-, S-(4-methoxyphenyl) ester(80472-59-9)
• EPA Substance Registry System: Benzenesulfonothioic acid, 4-methyl-, S-(4-methoxyphenyl) ester(80472-59-9)

Safety Data

• Hazardous Substances Data: 80472-59-9(Hazardous Substances Data)

Upstream product

• 100-66-3 methoxybenzene 
• 84655-87-8 SS-morpholino 4-toluene(dithioperoxo)sulfonate 
• 34764-82-4 morpholino p-toluenesulfonyl sulfide 
• 696-63-9 4-Methoxybenzenethiol 
• 459-44-9 4-methylbenzenediazonium tetrafluoroborate 
• 3753-27-3 sodium 4-methylbenzenesulfonothioate 
• 536-57-2 p-toluene sulfinic acid 
• 5335-87-5 4,4'-dimethoxyphenyl disulfide 
• 31819-04-2 p-methoxyphenyldisulfide 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 2943-42-2 di(4-methyl)phenylthiosulfonate 
• 80172-73-2 1-[(4-methoxyphenyl)sulfanyl]pyrrolidine-2,5-dione 
• 136400-98-1 S-(dimethylamino)-p-toluenethiosulfonate 

Downstream Products

• 113602-60-1 3-((4-methoxyphenyl)thio)thiophene 
• 2943-42-2 di(4-methyl)phenylthiosulfonate 
• 103-19-5 di(p-tolyl) disulfide 
• 158585-52-5 2,3-bis<(4-methoxyphenyl)thio>indole 
• 31570-54-4 Acetyl-p-methoxy-phenyldisulfid 
• 39248-96-9 S-(4-methoxyphenyl) 4-methylbenzothioate 
• 5633-57-8 1-methoxy-4-(phenylsulfanyl)benzene 
• 1314532-85-8 tert-butyl (3aS,4R,6S,6aR)-6-(2-(4-methoxyphenylthio)propan-2-yl)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ylcarbamate 
• 5335-87-5 4,4'-dimethoxyphenyl disulfide 
• 1879-16-9 1-methoxy-4-methylsulfanyl-benzene 

Relevant articles and documents

Acid-Mediated Sulfonylthiolation of Arenes via Selective Activation of SS-Morpholino Dithiosulfonate

A trifluoroacetic-acid-mediated desulfurilative sulfonylthiolation of arenes using SS-morpholino dithiosulfonate is described. This system is based on selective activation of the morpholino group over the tosyl group of the doubly transformable sulfur surrogate. Mechanistic studies suggested that the reaction proceeds through electrophilic aromatic substitution followed by sulfur extrusion. The wide substrate scope of this reaction and the transformability of the resulting thiosulfonates enable expeditious access to divergent multifunctionalized sulfides.

Atom transfer radical addition to styrenes with thiosulfonates enabled by synergetic copper/photoredox catalysis

A synergetic copper/photoredox catalyzed ATRA of styrenes and thiosulfonates is developed. Besides aryl ethylenes, the challenging α-substituted styrenes were employed to construct the benzylic quaternary carbon centers. Owing to the mild conditions as well as the high level of substrate compability, this ATRA could be applied to derivatize bioactive natural products in late stage, and to install fluorophores across alkenes. The mechanistic studies reveal sulfonyl radicals as the key intermediate in the transformation.

Organocatalytic Transformation of Aldehydes to Thioesters with Visible Light

A metal- and oxidant-free catalytic method for accessing structurally diverse thioesters from readily accessible, widespread aldehydes, is described. A strategy of a simple organic 9,10-phenanthrenequinone-promoted hydrogen atom transfer (HAT) with visible light was successfully implemented to selectively generate acyl radicals without inducing crossover reactivity of thioester products. The preparative power of the method was demonstrated by broad substrate scope and wide functional group tolerance, and enabled the late-stage modification of complex structures, which are difficult to achieve with the existing protocols.