805303-96-2

Basic information

• Product Name: 6-Chloro-N-(4-methoxy-benzyl)-nicotinamide
• Synonyms: 6-Chloro-N-(4-methoxy-benzyl)-nicotinamide
• CAS NO: 805303-96-2
• Molecular Formula: C₁₄H₁₃ClN₂O₂
• Molecular Weight: 277
• Mol File: 805303-96-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-Chloro-N-(4-methoxy-benzyl)-nicotinamide(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Chloro-N-(4-methoxy-benzyl)-nicotinamide(805303-96-2)
• EPA Substance Registry System: 6-Chloro-N-(4-methoxy-benzyl)-nicotinamide(805303-96-2)

Safety Data

• Hazardous Substances Data: 805303-96-2(Hazardous Substances Data)

Upstream product

• 5326-23-8 6-Chloro-3-pyridinecarboxylic acid 
• 2393-23-9 4-methoxy-benzylamine 
• 58757-38-3 6-Chloronicotinoyl chloride 

Downstream Products

• 1429253-86-0 C₂₃H₂₃N₃O₂ 
• 1429254-05-6 C₁₉H₂₃N₃O₂ 

Relevant articles and documents

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Weakly basic amines, including even neutral amines such as nitroaniline and aminocarboxylic acids, react with acid chlorides very efficiently in N, N -dimethylacetamide (DMAC), without addition of a base, to give the corresponding amides in high yields. The role of DMAC and related solvents as latent Bronsted bases was studied in these amidation reactions. Less basic amines, such as aromatic amines, reacted with benzoyl chloride faster than more basic aliphatic amines.

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