80595-16-0

Basic information

• Product Name: (1S)-1-phenyl-2-O-triphenylmethyl-1,2-ethanediol
• CAS NO: 80595-16-0
• Molecular Weight: 380.486
• Mol File: 80595-16-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1S)-1-phenyl-2-O-triphenylmethyl-1,2-ethanediol(CAS DataBase Reference)
• NIST Chemistry Reference: (1S)-1-phenyl-2-O-triphenylmethyl-1,2-ethanediol(80595-16-0)
• EPA Substance Registry System: (1S)-1-phenyl-2-O-triphenylmethyl-1,2-ethanediol(80595-16-0)

Safety Data

• Hazardous Substances Data: 80595-16-0(Hazardous Substances Data)

Upstream product

• 17199-29-0 (S)-Mandelic acid 
• 25779-13-9 (S)-1-phenyl-1,2-ethanediol 
• 76-83-5 trityl chloride 

Downstream Products

• 80595-19-3 C₅₈H₅₄O₅ 
• 80595-17-1 (S,S)-(+)-1,1,1,4,12,15,15,15-octaphenyl-2,5,8,11,14-pentaoxapentadecane 
• 685836-11-7 (1S)-1-O-allyl-1-phenyl-2-O-triphenylmethyl-1,2-ethanediol 
• 685836-12-8 (1S)-1-phenyl-1-O-(Z-prop-1'-en-1'-yl)-1,2-ethanediol 
• 95237-09-5 (1S)-1-O-allyl-1-phenyl-1,2-ethanediol 
• 685836-04-8 (1S,3'R,4'S)-2-O-methanesulfonyl-1-O-(3'-methyl-azetidin-2'-on-4'-yl)-1-phenyl-1,2-ethanediol 
• 685835-98-7 (1S)-1-phenyl-1-O-(Z-prop-1'-en-1'-yl)-2-O-(2,4,6-triisopropyl-benzenefulfonyl)-1,2-ethanediol 
• 685836-06-0 (1S,3'R,4'S)-1-O-(3'-methyl-azetidin-2'-on-4'-yl)-1-phenyl-2-O-(2,4,6-triisopropylbenzenesulfonyl)-1,2-ethanediol 
• 685836-05-9 (1S,3'S,4'R)-1-O-(3'-methyl-azetidin-2'-on-4'-yl)-1-phenyl-2-O-(2,4,6-triisopropylbenzenesulfonyl)-1,2-ethanediol 
• 80595-12-6 (S,S)-(+)-5,13-diphenyl-19-methoxy-3,6,9,12,15-pentaoxa-21-azabicyclo<15.3.1>heneicosa-1(21),17,19-triene-2,16-dione 
• 80595-14-8 (R,S)-2,10-diphenyl-3,6,9-trioxaundecane-1,11-diol 
• 80656-09-3 (R,R)-(-)-2,10-diphenyl-3,6,9-trioxaundecane-1,11-diol 
• 80656-05-9 (S,S)-(+)-9,17-diphenyl-1,4,7,10,13,16-hexaoxacyclooctadecane-2,6-dione 
• 80656-06-0 (S,S)-(+)-5,13-diphenyl-3,6,9,12,15,20-hexaoxabicyclo<15.2.1>eicosa-17,19-diene-2,6-dione 

Relevant articles and documents

Synthesis, biological, and chiroptical activity of 3-phenyl-clavams

The [2+2]cycloaddition of chlorosulfonyl isocyanate to simple vinyl ethers derived from the 2-O-sulfonylated (R) and (S) 1-phenyl-1,2-ethanediol leads to 4-alkoxy-azetidin-2-ones with a moderate stereoselectivity. The cycloaddition to analogous (Z)-propenyl ethers proceeds stereospecifically with the retention of the olefin configuration. The intramolecular alkylation of β-lactam nitrogen atom furnished all possible stereoisomers of 3-phenyl- and 6-methyl-3-phenyl-clavams. The biological and chiroptical activity of synthesized clavams was investigated. The (3R,5R)-diastereomer 30 showed higher inhibition of bacterial enzymes than other related compounds.