80628-86-0

Basic information

• Product Name: methyl (1S,6R,7R)-3-bromomethyl-1-oxo-7-phenoxyacetamido-3-cephem-4-carboxylate
• Synonyms: methyl (1S,6R,7R)-3-bromomethyl-1-oxo-7-phenoxyacetamido-3-cephem-4-carboxylate
• CAS NO: 80628-86-0
• Molecular Weight: 457.302
• Mol File: 80628-86-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl (1S,6R,7R)-3-bromomethyl-1-oxo-7-phenoxyacetamido-3-cephem-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (1S,6R,7R)-3-bromomethyl-1-oxo-7-phenoxyacetamido-3-cephem-4-carboxylate(80628-86-0)
• EPA Substance Registry System: methyl (1S,6R,7R)-3-bromomethyl-1-oxo-7-phenoxyacetamido-3-cephem-4-carboxylate(80628-86-0)

Safety Data

• Hazardous Substances Data: 80628-86-0(Hazardous Substances Data)

Upstream product

• 40143-52-0 methyl (1S,6R,7R)-3-methyl-1-oxo-7-phenoxyacetamido-3-cephem-4-carboxylate 
• 102-85-2 tri-n-butyl phosphite 

Downstream Products

• 37787-59-0 (6R)-3-methylene-5t,8-dioxo-7t-(2-phenoxy-acetylamino)-(6rH)-5λ⁴-thia-1-aza-bicyclo[4.2.0]octane-2c-carboxylic acid methyl ester 

Relevant articles and documents

Process for the preparation of 3-exomethylene cepham derivatives

A process is provided for the preparation of 3-methylene and 3-halomethylene cepham derivatives via 3-phosphoniomethyl-3-cephem derivatives, which in turn can be prepared from 3-halomethyl-3-cephem derivatives. The preparation can be carried out with or without isolating the intermediate phosphonium cephem compounds. The 3-methylene and 3-halomethylene cepham derivatives and in particular the 1-oxo and 1,1-dioxo cepham compounds are also prepared by reducing a 3-halomethyl-3-cephem derivative with activated metal, preferably zinc or magnesium.