80706-72-5

Basic information

• Product Name: Cyclobutanone, 2-acetyl- (9CI)
• Synonyms: Cyclobutanone, 2-acetyl- (9CI)
• CAS NO: 80706-72-5
• Molecular Formula: C₆H₈O₂
• Molecular Weight: 112.12652
• Product Categories: ACETYLGROUP
• Mol File: 80706-72-5.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cyclobutanone, 2-acetyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclobutanone, 2-acetyl- (9CI)(80706-72-5)
• EPA Substance Registry System: Cyclobutanone, 2-acetyl- (9CI)(80706-72-5)

Safety Data

• Hazardous Substances Data: 80706-72-5(Hazardous Substances Data)

Upstream product

• 80706-59-8 acetyl-2 oxaspiropentane 

Downstream Products

• 3128-06-1 5-ketohexanoic acid 
• 13984-50-4 methyl levulinate 

Relevant articles and documents

ETUDE DES PETITS CYCLES-XLIV. UNE VOIE DE SYNTHESE DES ACYL-2 CYCLOBUTANONES

Organic peracid oxidation of α-cyclopropylidene ketones and acetals substituted in the vinylic position leads to the corresponding oxaspiropentyl ketones and acetals.Esters are also formed from the products of the Baeyer-Villiger oxidation; they are easily removed from the crude product.Unsubstituted oxaspiropentyl ketones are not obtained by this method; they are obtained by oxidation of oxaspiropentyl alcohols ( formed by epoxidation of α-cyclopropylidene alcohols).The isomerisation, either spontaneous or through reaction with lithium halides, of oxaspiropentyl ketones and acetals, gives 2-acyl-cyclobutanones and corresponding mono-acetals.These new unstable 1,3-diones must be stored in CCl4 solution.They are present in the dione form only.They add water and methanol, in acidic and even in neutral medium, leading to ring opening products. 2-Benzoyl cyclobutanone 4g is easily rearranged into 3,4-dihydro-6-phenyl 2-pyrone 12.Deacetalization of the 2-acyl-cyclobutanones mono-acetals 7B-11b into the corresponding diones is not possible even by the moist silicagel technique.