80737-86-6

Basic information

• Product Name: Acetic acid, [(2-oxo-2-phenylethyl)thio]-, 1-methylethyl ester
• CAS NO: 80737-86-6
• Molecular Formula: C13H16O3S
• Molecular Weight: 252.334
• Mol File: 80737-86-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Acetic acid, [(2-oxo-2-phenylethyl)thio]-, 1-methylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, [(2-oxo-2-phenylethyl)thio]-, 1-methylethyl ester(80737-86-6)
• EPA Substance Registry System: Acetic acid, [(2-oxo-2-phenylethyl)thio]-, 1-methylethyl ester(80737-86-6)

Safety Data

• Hazardous Substances Data: 80737-86-6(Hazardous Substances Data)

Upstream product

• 7383-61-1 isopropyl 2-sulfanylacetate 
• 532-27-4 1-chloroacetophenone 
• 22536-46-5 2-((2-oxo-2-phenylethyl)thio)acetic acid 
• 67-63-0 isopropyl alcohol 
• 70-11-1 α-bromoacetophenone 
• 98-86-2 acetophenone 

Downstream Products

• 80737-90-2 isopropyl 3,6-dihydro-5-<oxy>-2H-thiopyran-2-carboxylate 
• 81134-62-5 isopropyl 3,6-dihydro-4-<oxy>-2H-thiopyran-2-carboxylate 
• 98-86-2 acetophenone 

Relevant articles and documents

An umpolung oxa-[2,3] sigmatropic rearrangement employing arynes for the synthesis of functionalized enol ethers

An oxa-[2,3] sigmatropic rearrangement involving arynes is reported featuring the umpolung of ketones, where the C=O bond polarity is reversed. The in situ-generated sulfur ylides from β-keto thioethers and arynes undergo efficient rearrangement allowing the facile and robust synthesis of functionalized enol ethers in high yields and excellent functional group compatibility. Preliminary mechanistic studies rule out the possibility of Pummerer-type rearrangement operating in this case.

Dienophilic Thioaldehydes

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