80755-86-8

Basic information

• Product Name: FIBRINOGEN GAMMA-CHAIN (397-411)
• Synonyms: H-GLY-GLN-GLN-HIS-HIS-LEU-GLY-GLY-ALA-LYS-GLN-ALA-GLY-ASP-VAL-OH;FIBRINOGEN RELATED PEPTIDE;FIBRINOGEN GAMMA-CHAIN (397-411);GLY-GLN-GLN-HIS-HIS-LEU-GLY-GLY-ALA-LYS-GLN-ALA-GLY-ASP-VAL;GQQHHLGGAKQAGDV;Fibrinogen g-Chain (397-411)
• CAS NO: 80755-86-8
• Molecular Formula: C62H99N23O21
• Molecular Weight: 1502.59
• Product Categories: peptide
• Mol File: 80755-86-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 2141.2±65.0 °C(Predicted)
• Appearance: /
• Density: 1.360±0.06 g/cm3(Predicted)
• Storage Temp.: -15°C
• PKA: 3.20±0.10(Predicted)
• CAS DataBase Reference: FIBRINOGEN GAMMA-CHAIN (397-411)(CAS DataBase Reference)
• NIST Chemistry Reference: FIBRINOGEN GAMMA-CHAIN (397-411)(80755-86-8)
• EPA Substance Registry System: FIBRINOGEN GAMMA-CHAIN (397-411)(80755-86-8)

Safety Data

• Hazardous Substances Data: 80755-86-8(Hazardous Substances Data)

Usage

Description

Fibrinogen gamma-chain (397-411) is a short peptide sequence derived from the gamma chain of fibrinogen, a glycoprotein present in plasma. This peptide sequence is essential for the initial stages of blood coagulation, as it plays a key role in the formation of fibrin clots. Fibrinogen gamma-chain (397-411) is involved in mediating the binding of fibrinogen to platelet integrin receptors, which is crucial for platelet aggregation and clot formation. Additionally, this peptide sequence has been found to have antimicrobial properties, suggesting a potential role in immune defense mechanisms. Studies have also shown that mutations in fibrinogen gamma-chain (397-411) can lead to clotting disorders and increased risk of thrombosis.

Uses

Used in Pharmaceutical Industry:
Fibrinogen gamma-chain (397-411) is used as a therapeutic agent for the treatment of clotting disorders and prevention of thrombosis. Its role in the formation of fibrin clots and binding to platelet integrin receptors makes it a potential candidate for the development of drugs targeting blood coagulation and clot formation.
Used in Immunology Research:
Fibrinogen gamma-chain (397-411) is used as a research tool in immunology for studying the antimicrobial properties of this peptide sequence. Its potential role in immune defense mechanisms can provide insights into the development of new strategies for combating infections and enhancing the immune response.
Used in Diagnostics:
Fibrinogen gamma-chain (397-411) can be used as a biomarker for the diagnosis of clotting disorders and the risk of thrombosis. Detection of mutations or abnormalities in this peptide sequence can help in the early identification of individuals at risk and guide appropriate treatment strategies.