80759-01-9Relevant articles and documents
Construction of the Bicyclooctane Ring System by an Intramolecular Diels-Alder Reaction - A Synthetic Approach to Atisane
Ihara, Masataka,Toyota, Masahiro,Fukumoto, Keiichiro,Kametani, Tetsuji,Honda, Toshio
, p. 2263 - 2277 (2007/10/02)
1,2,3,4-Tetrahydro-6,7-dimethoxy-1-(3-methoxybenzyl)-2-methylisoquinoline (3) was converted into the olefinic enone (7).After formation of the corresponding silyl enol ether (8), intramolecular Diels-Alder reaction of the triene (8) produced two stereoisomers of 3,10-ethano-3,4,4a,9,10,10a-hexahydro-6,7-dimethoxyphenanthren-2(1H)-one (9), one of which was transformed into the exomethylene (13) and the olefinic methyl compound (16).