80881-78-3

Basic information

• Product Name: 4H-1-Benzopyran-4-one,6-amino-2-(4-methoxyphenyl)-(9CI)
• Synonyms: 4H-1-Benzopyran-4-one,6-amino-2-(4-methoxyphenyl)-(9CI);6-amino-2-(4-methoxyphenyl)chromen-4-one
• CAS NO: 80881-78-3
• Molecular Formula: C₁₆H₁₃NO₃
• Molecular Weight: 267.27932
• Product Categories: FLAVONE
• Mol File: 80881-78-3.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4H-1-Benzopyran-4-one,6-amino-2-(4-methoxyphenyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzopyran-4-one,6-amino-2-(4-methoxyphenyl)-(9CI)(80881-78-3)
• EPA Substance Registry System: 4H-1-Benzopyran-4-one,6-amino-2-(4-methoxyphenyl)-(9CI)(80881-78-3)

Safety Data

• Hazardous Substances Data: 80881-78-3(Hazardous Substances Data)

Upstream product

• 80881-76-1 N-(2-(4-methoxyphenyl)-4-oxo-4H-chromen-6-yl)acetamide 
• 484008-63-1 2-O-(4-methoxy-benzoate)-5-acetamido-acetophenone 
• 100-07-2 4-methoxy-benzoyl chloride 
• 123-11-5 4-methoxy-benzaldehyde 
• 80881-74-9 4-Methoxy-2'-hydroxy-5'-acetamino-chalkon 
• 7298-67-1 5-acetamido-2-hydroxyacetophenone 

Relevant articles and documents

COMPOUNDS FOR THE TREATMENT OF AMYLOID-ASSOCIATED DISEASES

This invention provides novel compounds of formulae (I) or (II) or a stereoisomer, enantiomer, racemic, or tautomer thereof, (I) (II) wherein the substituents are as defined in the specification. The present invention also relates to the novel compounds for use as a medicine, more in particular for the prevention or treatment of amyloid-related diseases, more specifically certain neurological disorders, such as disorders collectively known as tauopathies, disorders characterized by cytotoxic α-synuclein amyloidogenesis. The present invention also relates to the use of said novel compounds for the manufacture of medicaments useful for treating such amyloid-related diseases. The present invention further relates to pharmaceutical compositions including said novel compounds and to methods for the preparation of said novel compounds.

Synthesis and complete assignment of the 1H and 13C NMR signals of new acetamido and aminoflavonoid derivatives

The complete 1H and13C NMR assignment of 9 acetamidochalcones, 18 acetamidoflavones, 18 aminoflavones, 9 acetamidoflavonols and 9 aminoflavonols has been performed using one- and two-dimensional NMR techniques including COSY, HMQC and HMBC experiments. Copyright

2-ARYL AND 2 -HETEROARYL 4H-1-BENZOPYRAN-4-ONE-6-AMIDINO DERIVATIVES FOR THE TREATMENT OF ARTHRITIS, CANCER AND RELATED PAIN

2-aryl and 2-heteroaryl 4h-1-benzopyran-4-one-6-amidino derivatives of formula (I) useful as pharmacological agents for the treatment of arthritis, cancer and related pain.