809272-94-4

Basic information

• Product Name: 3-Pyridinecarboxylicacid,5-hydroxy-4-(hydroxymethyl)-6-methyl-,ethylester(9CI)
• Synonyms: 3-Pyridinecarboxylicacid,5-hydroxy-4-(hydroxymethyl)-6-methyl-,ethylester(9CI)
• CAS NO: 809272-94-4
• Molecular Formula: C10H13NO4
• Molecular Weight: 0
• Product Categories: METHYL
• Mol File: 809272-94-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Pyridinecarboxylicacid,5-hydroxy-4-(hydroxymethyl)-6-methyl-,ethylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarboxylicacid,5-hydroxy-4-(hydroxymethyl)-6-methyl-,ethylester(9CI)(809272-94-4)
• EPA Substance Registry System: 3-Pyridinecarboxylicacid,5-hydroxy-4-(hydroxymethyl)-6-methyl-,ethylester(9CI)(809272-94-4)

Safety Data

• Hazardous Substances Data: 809272-94-4(Hazardous Substances Data)

Upstream product

• 2397-71-9 5-hydroxy-6-methylpyridine-3,4-dicarboxylic acid diethyl ester 

Relevant articles and documents

Silane reduction of 5-hydroxy-6-methyl-pyridine-3,4-dicarboxylic acid diethyl ester: Synthesis of vitamin B6

Alternative methods for the synthesis of pyridoxine have been investigated. The key intermediate, 5-hydroxy-6-methyl-pyridine-3,4-dicarboxylic acid diethyl ester (5), was reduced with either a silane monomer (MeSiH(OEt)2) or a polysiloxane (polymethylhydrosiloxane, PMHS) to afford crude pyridoxine. An isolation technique utilizing a commercially available resin was devised, affording the desired product, vitamin B6, in an overall yield of 38-54% and a purity of 76%.