80952-74-5

Basic information

• Product Name: dammaran-3,6,12,20,25-pentol-6-O-rhamnopyranosyl-(1-2)-O-glucopyranoside
• Synonyms: dammaran-3,6,12,20,25-pentol-6-O-rhamnopyranosyl-(1-2)-O-glucopyranoside
• CAS NO: 80952-74-5
• Molecular Formula: C42H74O14
• Molecular Weight: 803.02856
• Mol File: 80952-74-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: dammaran-3,6,12,20,25-pentol-6-O-rhamnopyranosyl-(1-2)-O-glucopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: dammaran-3,6,12,20,25-pentol-6-O-rhamnopyranosyl-(1-2)-O-glucopyranoside(80952-74-5)
• EPA Substance Registry System: dammaran-3,6,12,20,25-pentol-6-O-rhamnopyranosyl-(1-2)-O-glucopyranoside(80952-74-5)

Safety Data

• Hazardous Substances Data: 80952-74-5(Hazardous Substances Data)

Upstream product

• 52286-59-6 ginsenoside Re 

Relevant articles and documents

Method for preparing C25-hydroxyl aglucon and rare saponin of radix ginseng through metal ion catalysis

The invention discloses a method for preparing C25-hydroxyl aglucon and rare saponin of radix ginseng through metal ion catalysis. The method is simple in operation, low in cost and high in yield and purity and is applicable to large-batch production. According to the method, the C25-hydroxyl aglucon and rare saponin of the radix ginseng are prepared through catalytically hydrolyzing 20-O-glycosyl or saccharide chain of C20 of ginsenoside in a mixed solution of an organic solvent and water and catalytically adding water molecules to an unsaturated bond between C24 and C25 of the ginsenoside. The products can be applied to pharmaceutical development, radix ginseng products, healthy products and cosmetics.

Microbial transformation of 20(S)-protopanaxatriol-type saponins by Absidia coerulea

Three 20(S)-protopanaxatriol-type saponins, ginsenoside-Rg1 (1), notoginsenoside-R1 (2), and ginsenoside-Re (3), were transformed by the fungus Absidia coerulea (AS 3.3389). Compound 1 was converted into five metabolites, ginsenoside-Rh4 (4), 3β,2β,25- trihydroxydammar-(E)-20(22)-ene-6-O-β-D-glucopyranoside (5), 20(S)-ginsenoside-Rh1 (6), 20(R)-ginsenoside-Rh1 (7), and a mixture of 25-hydroxy-20(S)-ginsenoside-Rh1 and its C-20(R) epimer (8). Compound 2 was converted into 10 metabolites, 20(S)-notoginsenoside-R 2 (9), 20(R)-notoginsenoside-R2 (10), 3β,12β,25- trihydroxydammar-(E)-20(22)-ene-6-O-β-D-xylopyranosyl-(1→2) -β-D-glucopyranoside (11), 3β,12β-dihydroxydammar-(E)-20(22),24- diene-6-O-β-D-xylopyranosyl-(1→2)-β-D-glucopyranoside (12), 3β,12β,20,25-tetrahydroxydammaran-6-O-β-D-xylopyranosyl- (1→2)-β-D-glucopyranoside (13), and compounds 4-8. Compound 3 was metabolized to 20(S)-ginsenoside-Rg2 (14), 20(R)-ginsenoside-Rg 2 (15), 3β,12β,25-trihydroxydammar-(E)-20(22)-ene-6-O- α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside (16), 3β,12β-dihydroxydammar-(E)-20(22),24-diene-6-O-α-L- rhamnopyranosyl-(1→2)-β-D-glucopyranoside (17), 3β,12β,20, 25-tetrahydroxydammaran-6-O-α-L-rhamnopyranosyl-(1→2) -β-D-glucopyranoside (18), and compounds 4-8. The structures of five new metabolites, 10-13 and 16, were established by spectroscopic methods.