80967-16-4Relevant articles and documents
Visible-light promoted atom transfer radical addition?elimination (ATRE) reaction for the synthesis of fluoroalkylated alkenes using DMA as electron-donor
Xu, Wen-Wen,Wang, Le,Mao, Ting,Gu, Jiwei,Li, Xiao-Fei,He, Chun-Yang
supporting information, (2020/02/11)
Here, we describe a mild, catalyst-free and operationally-simple strategy for the direct fluoroalkylation of olefins driven by the photochemical activity of an electron donor?acceptor (EDA) complex between DMA and fluoroalkyl iodides. The significant advantages of this photochemical transformation are high efficiency, excellent functional group tolerance, and synthetic simplicity, thus providing a facile route for further application in pharmaceuticals and life sciences.
Organic Dye-Catalyzed Atom Transfer Radical Addition-Elimination (ATRE) Reaction for the Synthesis of Perfluoroalkylated Alkenes
Tiwari, Deo Prakash,Dabral, Saumya,Wen, Jian,Wiesenthal, Jan,Terhorst, Steven,Bolm, Carsten
supporting information, p. 4295 - 4298 (2017/08/23)
An atom transfer radical addition elimination (ATRE) reaction of terminal alkenes with perfluoroalkyl halides under visible light is described. The photoredox catalysis with Eosin Y provides perfluoroalkenes in good yields. The reaction has been utilized
An efficient synthesis of perfluoroalkenylated aryl compounds via Pincer-Pd catalyzed Heck couplings
Feng, Jie,Cai, Chun
, p. 6 - 10 (2013/03/28)
Heck couplings of aryl halides with fluoroalkyl-substituted ethylenes catalyzed by Pincer Palladium complex were described. A variety of fluorous ponytail-substituted aromatics were obtained with moderate to excellent yields. Moreover, the catalyst can be easily separated from the reaction mixture by F-SPE technique and reused three times without significant loss of activity.
