80998-07-8 Usage
Description
PHORBOL 12-N-METHYLANTHRANILATE, also known as Sapintoxin D, is a fluorescent and highly potent phorbol ester. It is a chemical compound consisting of phorbol that is acylated at positions 12 and 13 by 2-(methylamino)benzoyl and acetyl groups respectively. This unique structure endows it with various biological activities and potential applications in different fields.
Uses
Used in Pharmaceutical Industry:
PHORBOL 12-N-METHYLANTHRANILATE is used as a pharmacological tool for studying the mechanisms of protein kinase C (PKC) activation and signal transduction pathways. Its potent activity allows researchers to investigate the role of PKC in various cellular processes and diseases.
Used in Cancer Research:
In cancer research, PHORBOL 12-N-METHYLANTHRANILATE is used as a tumor promoter in the study of carcinogenesis and the development of cancer. Its ability to activate PKC and modulate signal transduction pathways makes it a valuable compound for understanding the molecular mechanisms underlying cancer progression.
Used in Neuroscience Research:
PHORBOL 12-N-METHYLANTHRANILATE is used as a research tool in neuroscience to investigate the role of PKC in neuronal function and synaptic plasticity. Its potent activity enables researchers to study the effects of PKC modulation on learning, memory, and other cognitive processes.
Used in Drug Development:
PHORBOL 12-N-METHYLANTHRANILATE is used as a lead compound in the development of new drugs targeting PKC-related diseases. Its unique structure and biological activity provide a foundation for designing and optimizing novel therapeutic agents with improved efficacy and selectivity.
Used in Analytical Chemistry:
Due to its fluorescent properties, PHORBOL 12-N-METHYLANTHRANILATE is used as a fluorescent probe in analytical chemistry for detecting and quantifying specific biomolecules or monitoring biochemical reactions. Its ability to emit fluorescence upon interaction with target molecules makes it a valuable tool for various analytical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 80998-07-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,9,9 and 8 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 80998-07:
(7*8)+(6*0)+(5*9)+(4*9)+(3*8)+(2*0)+(1*7)=168
168 % 10 = 8
So 80998-07-8 is a valid CAS Registry Number.
InChI:InChI=1/C30H37NO8/c1-15-11-22-28(36,24(15)34)13-18(14-32)12-20-23-27(4,5)30(23,39-17(3)33)25(16(2)29(20,22)37)38-26(35)19-9-7-8-10-21(19)31-6/h7-12,16,20,22-23,25,31-32,36-37H,13-14H2,1-6H3/t16-,20+,22-,23-,25-,28-,29-,30-/m1/s1
80998-07-8Relevant articles and documents
PARTIAL SYNTHESIS OF THE FLUORESCENT PHORBOL ESTER PROBE, SAPINTOXIN D
Brooks, G.,Morrice, N. A.,Aitken, A.,Evans, F. J.
, p. 1523 - 1524 (1988)
The partial synthesis of the novel fluorescent phorbol ester Sapintoxin D (12-O--phorbol-13-acetate), and its previously unreported C-20 acetate analogue, from phorbol is described.Sapintoxin D is a convenient fluorescent probe for t
