81067-46-1

Basic information

• Product Name: 1-CHLORO-3,5-DIBROMO-4-IODOBENZENE
• Synonyms: 1-CHLORO-3,5-DIBROMO-4-IODOBENZENE;4-Chloro-2,6-dibromoiodobenzene;3,5-Dibromo-4-iodochorobenzene;1,3-DibroMo-5-chloro-2-iodobenzene;5-Chloro-1,3-dibromo-2-iodobenzene
• CAS NO: 81067-46-1
• Molecular Formula: C₆H₂Br₂ClI
• Molecular Weight: 396.25
• Product Categories: Bromine Compounds;Chlorine Compounds;Iodine Compounds
• Mol File: 81067-46-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 109.6-110.2 °C(Solv: benzene (71-43-2); ethanol (64-17-5))
• Boiling Point: 327.04 °C at 760 mmHg
• Flash Point: 151.588 °C
• Appearance: /
• Density: 2.543 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.688
• CAS DataBase Reference: 1-CHLORO-3,5-DIBROMO-4-IODOBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-CHLORO-3,5-DIBROMO-4-IODOBENZENE(81067-46-1)
• EPA Substance Registry System: 1-CHLORO-3,5-DIBROMO-4-IODOBENZENE(81067-46-1)

Safety Data

• Hazardous Substances Data: 81067-46-1(Hazardous Substances Data)

Usage

General Description

1-Chloro-3,5-dibromo-4-iodobenzene is a multi-halogenated compound that belongs to the class of organic molecules known as haloarenes. 1-CHLORO-3,5-DIBROMO-4-IODOBENZENE consists of a benzene ring (a six-carbon ring with alternating double and single bonds) substituted with one chlorine, two bromine, and one iodine atoms at positions 1, 3, 5, and 4 respectively. These halogens constitute a significant part of the atomic structure of this compound and contribute to its physical and chemical properties. The compound is usually synthesized in the lab and not naturally occurring. It may be used in the synthesis of various other compounds in chemical industries or in laboratory research. Specific information regarding its toxicity and safety precautions should be found on its Material Safety Data Sheet (MSDS), as proper handling and disposal processes should be followed due to its potential reactivity and environmental effects.

InChI:InChI=1/C6H2Br2ClI/c7-4-1-3(9)2-5(8)6(4)10/h1-2H

Upstream product

• 106-47-8 4-chloro-aniline 
• 874-17-9 4-chloro-2,6-dibromoaniline 

Relevant articles and documents

Synthesis method of 1-bromo-3-chlorodibenzofuran

The invention belongs to the technical field of organic synthesis, and particularly discloses a novel synthesis method of 1-bromo-3-chlorodibenzofuran. According to the method, parachloroaniline is adopted as a raw material and firstly reacts with an N-bromosuccinimide (NBS) reagent to obtain a brominated product compound 2, then the compound 2 is subjected to a diazo-iodination reaction to obtain a compound 3, the compound 3 and o-methoxyphenylboronic acid are subjected to a suzuki coupling reaction to obtain a compound 4, methyl of the compound 4 is removed to obtain a compound 5, and finally, the compound 5 is subjected to intramolecular nucleophilic substitution reaction to obtain a final product. According to the method, cheap raw materials are used for replacing 4-chloro-2-fluoroaniline in the prior art, so that the production cost is greatly reduced; and the reaction yield of each step is high, the technological operation is simple, and the method is more suitable for industrial production.

Enantioposition-selective copper-catalyzed azide-alkyne cycloaddition for construction of chiral biaryl derivatives

A highly enantioposition-selective copper-catalyzed azide-alkyne cycloaddition (CuAAC) of dialkynes bearing prochiral biaryls has been developed for the construction of 1,2,3-triazoles bearing axially chiral biaryl groups in up to 76% yield and up to 99% ee.