81106-50-5

Basic information

• Product Name: Urea, N'-(2-bromophenyl)-N,N-dimethyl-
• CAS NO: 81106-50-5
• Molecular Formula: C9H11BrN2O
• Molecular Weight: 243.103
• Mol File: 81106-50-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Urea, N'-(2-bromophenyl)-N,N-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Urea, N'-(2-bromophenyl)-N,N-dimethyl-(81106-50-5)
• EPA Substance Registry System: Urea, N'-(2-bromophenyl)-N,N-dimethyl-(81106-50-5)

Safety Data

• Hazardous Substances Data: 81106-50-5(Hazardous Substances Data)

Upstream product

• 101-42-8 fenuron 
• 615-36-1 2-bromoaniline 
• 79-44-7 N,N-Dimethylcarbamoyl chloride 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 124-40-3 dimethyl amine 
• 1592-00-3 2-bromophenyl isocyanate 

Downstream Products

• 91-56-5 indole-2,3-dione 
• 101-42-8 fenuron 

Relevant articles and documents

Regioselective bromination of aryl ureas with Phenyliodine(III) diacetate and potassium bromide

An efficient regioselective and operationally simple urea bromination method utilizing PIDA and potassium bromide is reported. This protocol proved to be effective on a broad range of substituted ureas in acetone at room temperature, forming the p-brominated compounds in 44–86% yields.

Carbonylation of doubly lithiated N′-aryl-N,N-dimethylureas: A novel approach to isatins via intramolecular trapping of acyllithiums

Lithiation of N′-(2-bromoaryl)-N,N-dimethylureas with methyllithium and tert-butyllithium under nitrogen in anhydrous THF at 0°C gave doubly lithiated arylurea derivatives, which react with carbon monoxide at 0°C to give isatins in good yields. The scope of the reaction has been demonstrated by application to the synthesis of isatin itself and four substituted isatins beating alkyl, chloro or fluoro groups.