81114-98-9

Basic information

• Product Name: Chan's diene
• Synonyms: Chan's diene
• CAS NO: 81114-98-9
• Molecular Weight: 260.481
• Mol File: 81114-98-9.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Chan's diene(CAS DataBase Reference)
• NIST Chemistry Reference: Chan's diene(81114-98-9)
• EPA Substance Registry System: Chan's diene(81114-98-9)

Safety Data

• Hazardous Substances Data: 81114-98-9(Hazardous Substances Data)

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 62269-44-7 methyl 3-trimethylsiloxybut-2-enoate 
• 105-45-3 acetoacetic acid methyl ester 
• 26766-99-4 3-(trimethylsilanyloxy)but-2-enoic acid methyl ester 

Downstream Products

• 83467-67-8 C₃₁H₂₈O₁₀ 
• 52431-73-9 1,3,5-Trihydroxy-anthrachinon 
• 106225-84-7 2-(1'-benzyloxypentyl)-2,3-dihydro-6-methoxypyran-4-one 
• 66832-04-0 methyl 6-benzyloxy-5-hydroxy-3-oxodecanoate 
• 139068-40-9 (+) methyl (5S,6S)-6-benzyloxy-5-hydroxy-3-oxodecanoate 
• 104513-03-3 tetracenomycin B₂ 
• 1825-61-2 Trimethylmethoxysilane 
• 71009-08-0 Trimethylsilyl allene carboxylate 
• 176381-66-1 methyl (5R,6S)-(+)-6-(dibenzylamino)-5-hydroxy-3-oxo-7-phenylheptanoate 
• 176381-64-9 methyl (5R,6S)-(+)-6-(dibenzylamino)-5-hydroxy-7-methyl-3-oxooctanoate 
• 176381-65-0 methyl (5R,6S)-(-)-6-(dibenzylamino)-5-hydroxy-7,7-dimethyl-3-oxooctanoate 

Relevant articles and documents

New method for asymmetrically synthesizing natural product (-)-Euscapholide isomer

The invention relates to a new method for asymmetrically synthesizing a natural product (-)-Euscapholide isomer. The method comprises the following steps: carrying out methoxybenzyl group protection on (R)-3-hydroxymethyl butyrate used as an initial raw material, reducing by using diisobutylaluminium hydride, carrying out a Mukaiyama aldol reaction, reducing by using sodium borohydride, carrying out ring closure under acidic conditions, eliminating hydroxyl groups, and deprotecting to complete asymmetric total synthesis of the target molecule 1. The method has the advantages of novel and reasonable synthesis route design, cheap and easily available raw material, simple operating process, mild reaction conditions, efficient completion of the asymmetric total synthesis of the Euscapholide isomer with two chiral centers, and single product configuration.

Total synthesis of (±)-bisabosqual A

The synthesis of the novel squalene synthase inhibitor, bisabosqual A, was completed in 14 steps (longest linear sequence) from commercially available starting materials. The doubly convergent route employs a tandem 5-exo, 6-exo radical cyclization as the

Revision of the structure of alatinone to emodin

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