81223-73-6 Usage
General Description
Ethanone, 1-(1H-indol-6-yl)- (9CI) is a chemical compound with the molecular formula C11H9NO. It is a derivative of indole, a heterocyclic compound commonly found in nature and used in the synthesis of various pharmaceuticals and natural products. This specific compound is a ketone derivative of indole, with a carbonyl group attached to the first carbon atom of the indole ring. It is used in research and drug development for its potential biological activities and pharmacological properties, including its potential as an antitumor, antiviral, and antibacterial agent. Its detailed chemical and biological properties are areas of ongoing study and exploration.
Check Digit Verification of cas no
The CAS Registry Mumber 81223-73-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,2,2 and 3 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 81223-73:
(7*8)+(6*1)+(5*2)+(4*2)+(3*3)+(2*7)+(1*3)=106
106 % 10 = 6
So 81223-73-6 is a valid CAS Registry Number.
81223-73-6Relevant articles and documents
Electrophilic substitution of indole on the benzene moiety: A synthesis of 5-acyl- and 5-aroylindoles
Demopoulos, Vassilis J.,Nicolaou, Ioannis
, p. 1519 - 1522 (2007/10/03)
The Vilsmeier-Haack intermediate of indole is acylated, in the presence of a certain excess of AlCl3, exclusively at the benzene ring and especially at position-5. The formed acylindolecarboxaldehydes are readily decarbonylated on heating with Pd/C in mesitylene. Thus, 5-acylindoles and 5- aroylindoles are synthesized in a two step sequence from indole with overall yield of 30-46%.
