81281-96-1Relevant articles and documents
HYDROXYLATION OF ALKYL GROUPS ON THE PYRAZINE RING
Ohta, Akihiro,Ohta, Minoru
, p. 151 - 154 (2007/10/02)
Treatment of THF solutions of 2,5-dialkylpyrazine 1-oxides with oxygen in the presence of bases gave the corresponding 2-hydroxypyrazine 1-oxides and dimers.On the other hand, when 2-chloro-3,6-dialkylpyrazine 1-oxides and 3,6-dialkyl-2-hydroxypyrazine 1-oxides were treated under the same conditions, hydroxylation occurred successfully at the α-position of the side chain.