813433-76-0

Basic information

• Product Name: (S)-N-Boc-Morpholine-3-acetic acid
• Synonyms: (S)-N-Boc-3-(2-hydroxyethyl)morpholine;(S)-4-Boc-3-(2-hydroxyethyl)morpholine;(3S)-3-(2-Hydroxyethyl)-4-morpholinecarboxylic acid tert-butyl ester;(S)-tert-Butyl 3-(2-hydroxyethyl)morpholine-4-carboxylate;morpholine-4-carboxylate;-tert-Butyl 3-(2-hydroxyethyl);(S)-N-Boc-Morpholine-3-acetic acid
• CAS NO: 813433-76-0
• Molecular Formula: C11H21NO4
• Molecular Weight: 231.29
• Mol File: 813433-76-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 336℃
• Flash Point: 157℃
• Appearance: /
• Density: 1.097
• Vapor Pressure: 8.15E-06mmHg at 25°C
• Refractive Index: 1.474
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (S)-N-Boc-Morpholine-3-acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-N-Boc-Morpholine-3-acetic acid(813433-76-0)
• EPA Substance Registry System: (S)-N-Boc-Morpholine-3-acetic acid(813433-76-0)

Safety Data

• Hazardous Substances Data: 813433-76-0(Hazardous Substances Data)

Usage

General Description

(S)-N-Boc-Morpholine-3-acetic acid is a chemical compound notable for its two primary functional groups, the tert-butyloxycarbonyl (Boc) group and the morpholine ring. The Boc group is commonly used in organic chemistry to protect amines, making this compound important in organic synthesis processes. Morpholine rings, meanwhile, are significant in medicinal chemistry because they can increase the bioavailability of pharmaceutical drugs. The presence of the carboxylic acid group in the 3-position also makes this compound valuable for the synthesis of more complex organic molecules. It's mainly used in laboratories or industrial chemical reactions. Like all chemicals, it should be handled carefully with proper safety procedures followed.

InChI:InChI=1/C11H21NO4/c1-11(2,3)16-10(14)12-5-7-15-8-9(12)4-6-13/h9,13H,4-8H2,1-3H3/t9-/m0/s1

Upstream product

• 1000806-54-1 (E)-(4-tert-butoxycarbonylaminoethoxy)-2-butenal 
• 813433-72-6 (4-formyl-morpholin-3-yl)-acetic acid 
• 86236-84-2 2-(morpholin-3-yl)acetic acid 
• 81684-84-6 ethyl 2-(morpholin-3-yl)acetate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 761460-04-2 (3S)-4-tert-butoxycarbonyl-3-carbethoxymethylmorpholine 
• 761460-02-0 tert-Butyl 3-(2-ethoxy-2-oxoethyl)morpholine-4-carboxylate 

Relevant articles and documents

NOVEL IMIDAZOLE COMPOUND AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONIST

The present invention relates to a novel imidazole compound or a pharmaceutically acceptable salt thereof having a melanocortin receptor agonistic activity, and medical use thereof. The present invention relates to an imidazole compound represented by general formula [I] [wherein: Ring A represents an optionally substituted aryl group or the like; R1 represents a hydrogen atom, an optionally substituted alkyl group, or the like; R2 represents a hydrogen atom, a halogen atom, or the like; and R3 represents an optionally substituted alkyl group] or a pharmaceutically acceptable salt thereof.

Enantioselective organocatalytic intramolecular aza-Michael reaction: A concise synthesis of (+)-sedamine, (+)-allosedamine, and (+)-coniine

(Chemical Equation Presented) The intramolecular aza-Michael reaction of carbamates bearing remote α,β-unsaturated aldehydes under organocatalytic conditions took place with good yields and excellent ee's when Jorgensen catalyst IV was used in the process, giving rise to the enantioselective formation of several five- and six-membered heterocycles. The developed methodology was applied to the synthesis of three piperidine alkaloids.

An efficient synthesis of chiral cyclic β-amino acids via asymmetric hydrogenation

Cyclic β-amino acids, homoproline, homopipecolic acid and 3-carboxy-methylmorpholine were obtained in high enantiomeric excesses by transition metal-catalyzed asymmetric hydrogenation of cyclic β-acylamino-alkenoates. These compounds were synthesized by a