81441-25-0Relevant articles and documents
Synthesis, X-Ray Crystallographic Determination, and Opioid Activity of erythro-5-Methylmethadone Enantiomers. Evidence Which Suggests That μ and δ Opioid Receptors Possess Different Stereochemical Requirements
Portoghese, P. S.,Poupaert, J. H.,Larson, D. L.,Groutas, W. C.,Meitzner, G. D.,et al.
, p. 684 - 688 (1982)
Enantiomers of erythro-5-methylmethadone (3) were synthesized from optical antipodes of erythro-3-(dimethylamino)-2-butanol.X-ray crystallographic analysis of (-)-3 perchlorate revealed that it possesses the 5S,6S absolute configuration.It was found that