81520-06-1

Basic information

• Product Name: ((R)-4,4-Dibromo-2-methyl-but-3-enyloxymethyl)-benzene
• Synonyms: ((R)-4,4-Dibromo-2-methyl-but-3-enyloxymethyl)-benzene
• CAS NO: 81520-06-1
• Molecular Weight: 334.051
• Mol File: 81520-06-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ((R)-4,4-Dibromo-2-methyl-but-3-enyloxymethyl)-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: ((R)-4,4-Dibromo-2-methyl-but-3-enyloxymethyl)-benzene(81520-06-1)
• EPA Substance Registry System: ((R)-4,4-Dibromo-2-methyl-but-3-enyloxymethyl)-benzene(81520-06-1)

Safety Data

• Hazardous Substances Data: 81520-06-1(Hazardous Substances Data)

Upstream product

• 558-13-4 carbon tetrabromide 
• 79027-28-4 (2S)-3-(benzyloxy)-2-methylpropanal 
• 74924-27-9 methyl (S)-3-benzyloxy-2-methylpropanoate 
• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 
• 56506-90-2 (dibromomethyl)(triphenyl)phosphonium bromide 
• 81470-71-5 ((S)-3-tert-Butoxy-2-methyl-propoxymethyl)-benzene 
• 100-39-0 benzyl bromide 
• 63930-49-4 (R)-3-(benzyloxy)-2-methylpropan-1-ol 

Downstream Products

• 108393-28-8 (2S,3R,4S)-5-benzyloxy-2,3-dimethylpentane-1,4-diol 
• 81520-11-8 (2R,3S,4S)-5-(benzyloxy)-2,4-dimethylpentane-1,3-diol 
• 73814-75-2 [(2R,3S)-3-((S)-2-Benzyloxy-1-methyl-ethyl)-oxiranyl]-methanol 
• 73814-75-2 [(2S,3S)-3-((R)-2-Benzyloxy-1-methyl-ethyl)-oxiranyl]-methanol 
• 73814-74-1 (Z)-(R)-5-Benzyloxy-4-methyl-pent-2-en-1-ol 
• 81470-75-9 (Z)-(R)-5-Benzyloxy-4-methyl-pent-2-enoic acid methyl ester 
• 1361582-94-6 (R)-N-(4-(benzyloxy)-3-methylbut-1-yn-1-yl)-N-(3-bromobut-3-en-1-yl)-4-methylbenzenesulfonamide 
• 81470-74-8 (R)-5-Benzyloxy-4-methyl-pent-2-ynoic acid methyl ester 

Relevant articles and documents

Ynamide Carbopalladation: A Flexible Route to Mono-, Bi- and Tricyclic Azacycles

Bromoenynamides represent precursors to a diversity of azacycles by a cascade sequence of carbopalladation followed by cross-coupling/electrocyclization, or reduction processes. Full details of our investigations into intramolecular ynamide carbopalladation are disclosed, which include the first examples of carbopalladation/cross-coupling reactions using potassium organotrifluoroborate salts; and an understanding of factors influencing the success of these processes, including ring size, and the nature of the coupling partner. Additional mechanistic observations are reported, such as the isolation of triene intermediates for electrocyclization. A variety of hetero-Diels-Alder reactions using the product heterocycles are also described, which provide insight into Diels-Alder regioselectivity.

Further synthetic studies on rifamycin S

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