81531-47-7

Basic information

• Product Name: [(S)-2-((S)-3-Benzyl-1,4-dioxo-hexahydro-pyrrolo[1,2-a]pyrazin-2-yl)-1-benzyloxymethyl-2-oxo-ethyl]-carbamic acid tert-butyl ester
• CAS NO: 81531-47-7
• Molecular Weight: 521.613
• Mol File: 81531-47-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: [(S)-2-((S)-3-Benzyl-1,4-dioxo-hexahydro-pyrrolo[1,2-a]pyrazin-2-yl)-1-benzyloxymethyl-2-oxo-ethyl]-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [(S)-2-((S)-3-Benzyl-1,4-dioxo-hexahydro-pyrrolo[1,2-a]pyrazin-2-yl)-1-benzyloxymethyl-2-oxo-ethyl]-carbamic acid tert-butyl ester(81531-47-7)
• EPA Substance Registry System: [(S)-2-((S)-3-Benzyl-1,4-dioxo-hexahydro-pyrrolo[1,2-a]pyrazin-2-yl)-1-benzyloxymethyl-2-oxo-ethyl]-carbamic acid tert-butyl ester(81531-47-7)

Safety Data

• Hazardous Substances Data: 81531-47-7(Hazardous Substances Data)

Upstream product

• 23680-31-1 BOC-O-benzyl-L-serine 
• 3705-26-8 L-Phenylalanyl-L-prolin-lactam 
• 54793-80-5 (S)-proline-(S)-phenylalanine methyl ester 
• 23631-72-3 N-carbobenzoxy-L-prolyl-L-phenylalanine methyl ester 
• 23680-31-1 O-benzyl-N-(tert-butoxycarbonyl)serine 
• 5654-85-3 (3S,8aS)-3-benzyloctahydropyrrolo[1,2-a]pyrazine-1,4-dione 

Downstream Products

• 81531-46-6 N-(9,10-Dihydrolysergyl-O-benzyl-L-seryl)-L-phenylalanyl-L-prolin-lactam 
• 82537-92-6 [(S)-2-((S)-3-Benzyl-1,4-dioxo-hexahydro-pyrrolo[1,2-a]pyrazin-2-yl)-1-hydroxymethyl-2-oxo-ethyl]-carbamic acid tert-butyl ester 

Relevant articles and documents

Improved Synthetic Pathways to the Cyclol System of Ergot Peptide Alkaloids

As demonstrated in the case of N-tert.butyloxycarbonylhydroxyglycine, N-protected 2-hydroxy-2-amino acids can be directly condensed with dipeptide esters to afford tripeptide derivatives, which are activated C-terminally and transferred into the epimers (