81539-57-3Relevant articles and documents
Inhibitors of the interaction of a thyroid hormone receptor and coactivators: Preliminary structure-activity relationships
Arnold, Leggy A.,Kosinski, Aaron,Estébanez-Perpi?á, Eva,Fletterick, Robert J.,Guy, R. Kiplin
, p. 5269 - 5280 (2008/03/12)
The modulation of gene regulation by blocking the interaction between the thyroid receptor (TR) and obligate coregulators has been reported recently with the discovery of the lead compound 3-(dimethylamino)-1-(4-hexylphenyl)propan-1- one). Herein we repor