81585-31-1

Basic information

• Product Name: 5-Pyrimidinecarbonitrile, hexahydro-4-(4-methoxyphenyl)-6-oxo-2-thioxo-
• CAS NO: 81585-31-1
• Molecular Formula: C12H11N3O2S
• Molecular Weight: 261.304
• Mol File: 81585-31-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 5-Pyrimidinecarbonitrile, hexahydro-4-(4-methoxyphenyl)-6-oxo-2-thioxo-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Pyrimidinecarbonitrile, hexahydro-4-(4-methoxyphenyl)-6-oxo-2-thioxo-(81585-31-1)
• EPA Substance Registry System: 5-Pyrimidinecarbonitrile, hexahydro-4-(4-methoxyphenyl)-6-oxo-2-thioxo-(81585-31-1)

Safety Data

• Hazardous Substances Data: 81585-31-1(Hazardous Substances Data)

Upstream product

• 2286-29-5 ethyl 2-cyano-3-(4-methoxyphenyl)prop-2-enoate 
• 17356-08-0 thiourea 
• 50897-91-1 ethyl 2-cyano-3-(4-methoxyphenyl)-acrylate 
• 2826-26-8 2-(4-methoxyphenylmethylene)malononitrile 
• 154198-90-0 (E)-3-p-anisyl-2-cyano-2-propenoyl azide 
• 27888-23-9 (E)-3-p-anisyl-2-cyano-2-propenoyl chloride 
• 2017-87-0 ethyl (2E)-2-cyano-3-(4-methoxyphenyl)acrylate 

Downstream Products

• 138608-97-6 C₁₆H₁₅N₃O₄S 
• 1096712-77-4 C₁₂H₁₀ClN₃OS 
• 70638-54-9 5-cyano-4-oxo-6-(4-methoxyphenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine 

Relevant articles and documents

Synthesis of some new pyrimidine and pyrimido[4,5-d]pyrimidine derivatives

A convenient synthesis of a series of pyrimidine carbonitrile, thiopyrimidine, and pyrimidopyrimidine derivatives, via the reactions of the versatile, readily accessible 6-aryl-4-oxo-2-thioxo-hexahydro-pyrimidine-5- carbonitrile with the appropriate reagents, is described. Copyright Taylor & Francis Group, LLC.

An efficient synthesis of 4-oxo-2-thioxohexahydropyrimidines

Several 4-oxo-2-thioxohexahydropyrimidines have been synthesised in very good yields from ethyl 2-cyanopropenoates and thiourea in sodium methoxide-methanol medium.

SYNTHESIS OF HETEROCYCLIC COMPOUNDS XXII. PREPARATION OF 6-ARYL-2-THIOXOPYRIMIDINES

The reactions of different ethyl benzylidenecyanoacetates (I) and benzylidenemalononitriles (V) with thiourea in an alcohol-alkoxide medium, provide a new and simple method for the synthesis of 6-aryl-5-cyano-4-oxo-2-thioxohexahydropyrimidines (III) and 4