816424-31-4

Basic information

• Product Name: 2-{[(3R)-3-aminopyrrolidin-1-yl]carbonyl}-3-[(2,4-difluorophenyl)amino]-7-phenylthieno[2,3-b]pyridin-6(7H)-one
• Synonyms: 2-{[(3R)-3-aminopyrrolidin-1-yl]carbonyl}-3-[(2,4-difluorophenyl)amino]-7-phenylthieno[2,3-b]pyridin-6(7H)-one
• CAS NO: 816424-31-4
• Molecular Weight: 466.511
• Mol File: 816424-31-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-{[(3R)-3-aminopyrrolidin-1-yl]carbonyl}-3-[(2,4-difluorophenyl)amino]-7-phenylthieno[2,3-b]pyridin-6(7H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{[(3R)-3-aminopyrrolidin-1-yl]carbonyl}-3-[(2,4-difluorophenyl)amino]-7-phenylthieno[2,3-b]pyridin-6(7H)-one(816424-31-4)
• EPA Substance Registry System: 2-{[(3R)-3-aminopyrrolidin-1-yl]carbonyl}-3-[(2,4-difluorophenyl)amino]-7-phenylthieno[2,3-b]pyridin-6(7H)-one(816424-31-4)

Safety Data

• Hazardous Substances Data: 816424-31-4(Hazardous Substances Data)

Upstream product

• 639482-02-3 pentafluorophenyl 3-[(2,4-difluorophenyl)amino]-6-oxo-7-phenyl-6,7-dihydrothieno[2,3-b]pyridine-2-carboxylate 
• 103831-11-4 (3R)-3-aminopyrrolidine dihydrochloride 

Relevant articles and documents

THIENOPYRIDONE DERIVATIVES AS KINASE INHIBITORS

A series of thieno[2,3-b]pyridin-6(7H)-one derivatives, substituted in the 2-position by a carbonyl- or sulfonyl-linked pyrrolidin-1-yl or related moiety, being inhibitors of p38 MAP kinase, are accordingly of use in medicine, for example in the treatment