816454-31-6

Basic information

• Product Name: 4-Phenoxy-1H-indazol-3-ylamine
• Synonyms: 3-Amino-4-phenoxy-1H-indazole;4-Phenoxy-1H-indazol-3-ylamine;4-Phenoxy-1H-indazol-3-amine;1H-Indazol-3-aMine,4-phenoxy-
• CAS NO: 816454-31-6
• Molecular Formula: C₁₃H₁₁N₃O
• Molecular Weight: 225.24594
• Mol File: 816454-31-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Phenoxy-1H-indazol-3-ylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Phenoxy-1H-indazol-3-ylamine(816454-31-6)
• EPA Substance Registry System: 4-Phenoxy-1H-indazol-3-ylamine(816454-31-6)

Safety Data

• Hazardous Substances Data: 816454-31-6(Hazardous Substances Data)

Upstream product

• 175204-06-5 2-phenoxy-6-fluorobenzonitrile 

Downstream Products

• 816454-27-0 N-(2,5-dimethoxybenzyl)-4-phenoxy-1H-indazol-3-amine 

Relevant articles and documents

3-AMINOINDAZOLES

Novel 3-aminoindazoles of formula (I) are SGK-inhibitors and can be used for treating SGK-related diseases and illnesses such as diabetes, obesity, metabolic syndrome (dyslipidaemia), systemic and pulmonary hypertonia, cardiovascular diseases and renal diseases, and generally any type of fibroses and inflammatory processes.

INDAZOLE/PYRZOLO[4,3-c]PYRIDIN DERIVATIVES AS JNK INHIBITORS, COMPOSITIONS AND METHODS RELATED THERETO AS WELL AS INTERMEDIATE THEREOF

The present invention relates to new compounds of formula (I) in which:X is CR4 or N; R1 is -OR5, -NHCOR6 or -NR6R7; R2 is hydrogen, Oar1 or -NHAr1 wherein Ar1 is aryl optionally substituted with one or more of R8, -OR8, -NR8R9, -CONR8R9, -COOR8, -NR8COR9, -SR8, -SO2NR8R9, -NR8SO2 R9, halogen, cyano, or nitro; R3 is hydrogen or -NHAr2 wherein Ar2 is benzene optionally substituted with one or more of R8, -OR8, -NR8R9, halogen or nitro, wherein R2 and R3 is not simultaneously hydrogen; a process for their preparation and new intermediates used therein, pharmaceutical formulations containing said therapeutically active compounds and to the use of said active compounds in therapy.