816454-86-1 Usage
Chemical class
Indazole derivatives
Structure
Indazole ring with an amine group at the 3-position and a 4-(4-fluorophenoxy) substituent at the 4-position
Potential applications
Pharmaceutical research and drug development, particularly in the field of medicinal chemistry
Influence of fluoro-substituent
Can significantly impact bioactivity
Value in drug design
Valuable target for drug design and discovery
Unique characteristics
Promising candidate for further investigation and potential therapeutic use.
Check Digit Verification of cas no
The CAS Registry Mumber 816454-86-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,1,6,4,5 and 4 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 816454-86:
(8*8)+(7*1)+(6*6)+(5*4)+(4*5)+(3*4)+(2*8)+(1*6)=181
181 % 10 = 1
So 816454-86-1 is a valid CAS Registry Number.
816454-86-1Relevant articles and documents
Structure-driven HtL: Design and synthesis of novel aminoindazole inhibitors of c-Jun N-terminal kinase activity
Stocks, Michael J.,Barber, Simon,Ford, Rhonan,Leroux, Frederic,St-Gallay, Steve,Teague, Simon,Xue, Yafeng
, p. 3459 - 3462 (2005)
The design and synthesis of a new series of c-Jun N-terminal kinase inhibitors are reported. The novel series of substituted amino indazoles were designed based on a combination of hits from high-throughput screening and X-ray crystal structure informatio
