816458-63-6Relevant articles and documents
N-H insertion reactions of Boc-amino acid amides: Solution- and solid-phase synthesis of pyrazinones and pyrazines
Matsushita, Hana,Lee, Sang-Hyeup,Yoshida, Kazuhiro,Clapham, Bruce,Koch, Guido,Zimmermann, Juerg,Janda, Kim D.
, p. 4627 - 4629 (2007/10/03)
(Chemical equation presented) A series of α-diazo-β-ketoesters were reacted with Boc amino acid amides in the presence of rhodium octanoate catalyst. The resulting N-H insertion products were treated with acid, providing the 1,4-azine intermediates, which