81718-77-6 Usage
Description
5-METHOXY-3-METHYL-BENZOFURAN-2-CARBOXYLIC ACID is a benzofuran derivative that features a carboxylic acid group and is known for its potential therapeutic properties. This chemical compound, belonging to the benzofuran class, has gained attention in medical and pharmaceutical research due to its promising biological activities.
Uses
Used in Pharmaceutical Research:
5-METHOXY-3-METHYL-BENZOFURAN-2-CARBOXYLIC ACID is used as a potential therapeutic agent for various conditions due to its anti-inflammatory, antimicrobial, and anticancer properties. The presence of methoxy and methyl groups in its structure likely enhances these biological activities, making it a candidate for drug development.
Used in Anti-Inflammatory Applications:
In the medical field, 5-METHOXY-3-METHYL-BENZOFURAN-2-CARBOXYLIC ACID is used as an anti-inflammatory agent, helping to reduce inflammation and associated symptoms.
Used in Antimicrobial Applications:
5-METHOXY-3-METHYL-BENZOFURAN-2-CARBOXYLIC ACID is utilized as an antimicrobial agent, working to combat microbial infections and contributing to the development of new antibiotics.
Used in Anticancer Applications:
In oncology, 5-METHOXY-3-METHYL-BENZOFURAN-2-CARBOXYLIC ACID is employed as a potential anticancer agent, being studied for its ability to target and inhibit cancer cell growth and proliferation.
Check Digit Verification of cas no
The CAS Registry Mumber 81718-77-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,7,1 and 8 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 81718-77:
(7*8)+(6*1)+(5*7)+(4*1)+(3*8)+(2*7)+(1*7)=146
146 % 10 = 6
So 81718-77-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H10O4/c1-6-8-5-7(14-2)3-4-9(8)15-10(6)11(12)13/h3-5H,1-2H3,(H,12,13)
81718-77-6Relevant articles and documents
Benzofuran Derivatives. Part 4. Synthesis of Benzofurans and 2,3,4,5-Tetrahydro-1-benzoxepin-3,5-diones
Suzuki, Tsuneo,Tanemura, Kiyoshi,Horaguchi, Takaaki,Shimimizu, Takahachi,Sakakibara, Tohru
, p. 423 - 429 (2007/10/02)
By treatment of ethyl 4- or 5-substituted 2-acetylphenoxyacetates 1 with potassium hydroxide in dry dioxane, benzofurans 2-7 and 2,3,4,5-tetrahydro-1-benzoxepin-3,5-diones 8 were obtained.The relative yields of benzofurans 2-7 and 2,3,4,5-tetrahydro-1-benzoxepin-3,5-diones 8 varied with the types of 4- or 5-substituents.The electron-donating 4-methoxyl group favored the formation of benzoxepins.On the other hand, electron-withdrawing substituents such as the 4-nitro group favored the formation of benzofurans.When esters 1 were treated with sodium amide,2,3-dihydrobenzofurans 2 were obtained exclusively regardless of 4- or 5-substituents.
METHODS FOR THE HOMOLOGATION OF BENZOFURANCARBOXYLIC ACIDS USING DIANIONIC INTERMEDIATES
Buttery, Cheryl D.,Knight, David W.,Nott, Andrew P.
, p. 4127 - 4130 (2007/10/02)
Dianions (2), (5), and (10), can be derived from the corresponding benzofurancarboxylic acids using lithium diisopropylamide, and are useful intermediates for the homologation of the parent acids.
