81720-20-9

Basic information

• Product Name: Acetic acid, (3-methoxyphenoxy)-, methyl ester
• CAS NO: 81720-20-9
• Molecular Formula: C10H12O4
• Molecular Weight: 196.203
• Mol File: 81720-20-9.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: Acetic acid, (3-methoxyphenoxy)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, (3-methoxyphenoxy)-, methyl ester(81720-20-9)
• EPA Substance Registry System: Acetic acid, (3-methoxyphenoxy)-, methyl ester(81720-20-9)

Safety Data

• Hazardous Substances Data: 81720-20-9(Hazardous Substances Data)

Upstream product

• 96-35-5 glycolic acid methyl ester 
• 766-85-8 3-methoxy-1-iodobenzene 
• 150-19-6 O-methylresorcine 
• 96-32-2 bromoacetic acid methyl ester 
• 96-34-4 methyl chloroacetate 
• 67-56-1 methanol 
• 2088-24-6 3-methoxyphenoxyacetic acid 

Downstream Products

• 1448524-07-9 N-[(4-methoxy-2-methylphenylcarbamoyl)methyl]-2-(3-methoxyphenoxy)acetamide 
• 1267237-09-1 C₁₂H₁₂N₂O₃ 
• 189574-46-7 m-methoxyphenoldimethyl 3-methoxyphenoxymalonate 
• 135360-59-7 N-acetoxy-N-<2-(3-methoxyphenoxy)ethyl>acetamide 
• 135360-68-8 N-hydroxy-N-<(3-methoxyphenoxy)ethyl>acetamide 
• 135360-49-5 (3-methoxyphenoxy)acetaldoxime 
• 436155-51-0 phenyl 2-[2-(3-methoxyphenoxy)acetyl]hydrazinecarboxylate 
• 55364-67-5 6-methoxy-2-benzofurancarboxylic acid methyl ester 
• 436155-36-1 2-(3-methoxyphenoxy)acetylhydrazine 
• 135360-34-8 2-(3-METHOXYPHENOXY)ACETALDEHYDE 
• 2088-24-6 3-methoxyphenoxyacetic acid 

Relevant articles and documents

Design and Synthesis of Novel 4-Hydroxyl-3-(2-phenoxyacetyl)-pyran-2-one Derivatives for Use as Herbicides and Evaluation of Their Mode of Action

In order to develop a novel herbicide containing the β-triketone motif, a series of 4-hydroxyl-3-(2-phenoxyacetyl)-pyran-2-one derivatives were designed and synthesized. The bioassay results showed that compound II15 had good pre-emergent herbicidal activity even at a dosage of 187.5 g ha-1. Moreover, compound II15 showed a broader spectrum of weed control when compared with a commercial herbicide 2,4-dichlorophenoxyacetic acid (2,4-D), and displayed good crop safety to Triticum aestivum L. and Zea mays Linn. when applied at 375 g ha-1 under pre-emergence conditions, which indicated its great potential as a herbicide. More importantly, studying the molecular mode of action of compound II15 revealed that the novel triketone structure is a proherbicide of its corresponding phenoxyacetic acid auxin herbicide, which has a herbicidal mechanism similar to that of 2,4-D. The present work indicates that the 4-hydroxyl-3-(2-phenoxyacetyl)-pyran-2-one motif may be a potential lead structure for further development of novel auxin-type herbicides.

In silico and pharmacological screenings identify novel serine racemase inhibitors

d-Serine is a coagonist of the N-methyl-d-aspartate (NMDA)-type glutamate receptor and its biosynthesis is catalyzed by serine racemase (SR). The overactivation of the NMDA receptor has been implicated in the development of neurodegenerative diseases, strokes, and epileptic seizures, thus, the inhibitors of SR have potential against these pathological states. Here, we have developed novel inhibitors of SR by in silico screening and in vitro enzyme assay. The newly developed inhibitors have lower IC50 value comparing with that of malonate, one of the standard SR inhibitor. The structural features of novel inhibitors suggest the importance of central amide structure having a phenoxy substituent in their structure for the SR inhibitory activity. The present findings suggest the importance and rational development of new drugs for diseases of NMDAR overactivation.

Biaryl-propionic acid derivatives and their use as pharmaceuticals

The present invention relates to compounds of the formula I, wherein X, R, R1, R2, D, E1, E2, E3, E4, G1, G2, G3 and G4 have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. They are inhibitors of the protease cath