817575-50-1Relevant articles and documents
A chemoselective microwave-assisted one-pot cross-stille reaction of benzylic halides with 2(1H)-pyrazinones using simultaneous cooling
Appukkuttan, Prasad,Husain, Mofazzal,Gupta, Rajinder K.,Parmar, Virinder S.,Van Der Eycken, Erik
, p. 1491 - 1496 (2006)
This manuscript reports the chemoselective one-pot cross-Stille coupling of benzylic halides with 3,5-dichloro-2(1H)-pyrazinones, which avoids the purification and handling of toxic stannylated intermediates. Significant improvements in yields were established when microwave irradiation was performed with simultaneous cooling. Georg Thieme Verlag Stuttgart.
Design and synthesis of novel type VI-like β-turn mimetics. Diversity at the i+1 and the i+2 position
De Borggraeve, Wim M.,Verbist, Bie M.P.,Rombouts, Frederik J.R.,Pawar, Vijaykumar G.,Smets, Wim J.,Kamoune, Laila,Alen, Jo,Van Der Eycken, Erik V.,Compernolle, Frans,Hoornaert, Georges J.
, p. 11597 - 11612 (2007/10/03)
In this paper, a synthetic approach for functionalised 5-aminopiperidinone- 2-carboxylate (APC) systems as non-pro cis-peptide bond containing external β-turn mimics is presented. The scope and limitations of the synthetic method are discussed and the pot
